A review on preparation and chemical analysis of postbiotics from lactic acid bacteria

Postbiotics may be defined as soluble metabolites released by food-grade microorganisms during the growth and fermentation in complex microbiological culture, food or gut. It is rich in high and low molecular weight biologically active metabolites. There are still gaps concerning these substances, mainly how to use them for food applications. Although the most recent work on preparation and application of postbiotics from several probiotics are very encouraging, the suitability of postbiotics to combat microorganisms that deal with food safety should be tested mainly by analyzing the chemical composition and conducting antagonistic tests. Consequently, foods can effectively benefit from an identified postbiotic with a defined effect. This review approached the recent advances in relation to the preparation of postbiotics from lactic acid bacteria. The function of different instrumental analysis techniques and factors affecting the chemical composition of postbiotics were also comprehensively reviewed.

Automated summary

Postbiotics are soluble metabolites released by food-grade microorganisms during growth and fermentation, rich in biologically active compounds of varying molecular weights. While recent research on preparing and using postbiotics from probiotics is encouraging, their effectiveness against foodborne microorganisms requires further testing through chemical analysis and antagonistic tests.