Related references
Note: Only part of the references are listed.Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
Yi Zhou et al.
IMMUNITY (2020)
STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment
Steven Lohard et al.
NATURE COMMUNICATIONS (2020)
The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer
John Kwon et al.
CANCER DISCOVERY (2020)
Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity
Linda Schadt et al.
CELL REPORTS (2019)
Cytosolic DNA Sensing in Organismal Tumor Control
Claire Vanpouille-Box et al.
CANCER CELL (2018)
The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer
Tuo Li et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
cGAS-STING and Cancer: Dichotomous Roles in Tumor Immunity and Development
Kevin W. Ng et al.
TRENDS IN IMMUNOLOGY (2018)
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer
Magalie Dosset et al.
ONCOIMMUNOLOGY (2018)
The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
Wen Pan et al.
IMMUNITY (2017)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Shane M. Harding et al.
NATURE (2017)
Cytoplasmic chromatin triggers inflammation in senescence and cancer
Zhixun Dou et al.
NATURE (2017)
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
Selene Gluck et al.
NATURE CELL BIOLOGY (2017)
cGAS is essential for the antitumor effect of immune checkpoint blockade
Hua Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
An Update on Randomized Clinical Trials in Metastatic Colorectal Carcinoma
Naruhiko Ikoma et al.
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2017)
miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism
Jun Liu et al.
BLOOD (2017)
STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
Henrique Lemos et al.
CANCER RESEARCH (2016)
The cGAS-STING Defense Pathway and Its Counteraction by Viruses
Zhe Ma et al.
CELL HOST & MICROBE (2016)
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Qing Chen et al.
NATURE (2016)
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing
Qi Chen et al.
NATURE IMMUNOLOGY (2016)
The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations
Katrina Meeth et al.
PIGMENT CELL & MELANOMA RESEARCH (2016)
A Molecular Chipper technology for CRISPR sgRNA library generation and functional mapping of noncoding regions
Jijun Cheng et al.
NATURE COMMUNICATIONS (2016)
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
Tianli Xia et al.
CELL REPORTS (2016)
STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia
Emily Curran et al.
CELL REPORTS (2016)
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Valentina Cappello et al.
SCIENTIFIC REPORTS (2016)
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents
Lorenzo Galluzzi et al.
CANCER CELL (2015)
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
David Roulois et al.
CELL (2015)
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Katherine B. Chiappinelli et al.
CELL (2015)
Mitochondrial DNA stress primes the antiviral innate immune response
A. Phillip West et al.
NATURE (2015)
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
Olivier Demaria et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
Leticia Corrales et al.
CELL REPORTS (2015)
Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
Michael J. White et al.
CELL (2014)
Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA
Anthony Rongvaux et al.
CELL (2014)
Nonstochastic Reprogramming from a Privileged Somatic Cell State
Shangqin Guo et al.
CELL (2014)
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Seng-Ryong Woo et al.
IMMUNITY (2014)
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Liufu Deng et al.
IMMUNITY (2014)
The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
Xin Cai et al.
MOLECULAR CELL (2014)
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
Antonella Sistigu et al.
NATURE MEDICINE (2014)
Inflammation-driven carcinogenesis is mediated through STING
Jeonghyun Ahn et al.
NATURE COMMUNICATIONS (2014)
The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome
S. M. Robinson et al.
BRITISH JOURNAL OF CANCER (2013)
Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance
Laurence Zitvogel et al.
IMMUNITY (2013)
The Cancer Genome Atlas Pan-Cancer analysis project
John N. Weinstein et al.
NATURE GENETICS (2013)
Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium
Matthew J. Ellis et al.
CANCER DISCOVERY (2013)
An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis
Jijun Cheng et al.
CELL REPORTS (2013)
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms
Shangqin Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
An In Vivo Functional Screen Uncovers miR-150-Mediated Regulation of Hematopoietic Injury Response
Brian D. Adams et al.
CELL REPORTS (2012)
Molecular signatures database (MSigDB) 3.0
Arthur Liberzon et al.
BIOINFORMATICS (2011)
Gene expression signature and response to the use of leucovorin, fluorouracil and oxaliplatin in colorectal cancer patients
Toshiaki Watanabe et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2011)
5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity
Julie Vincent et al.
CANCER RESEARCH (2010)
5-fluorouracil: Mechanisms of resistance and reversal strategies
Ning Zhang et al.
MOLECULES (2008)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
5-Fluorouracil: Mechanisms of action and clinical strategies
DB Longley et al.
NATURE REVIEWS CANCER (2003)
Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells
N Takebe et al.
CANCER GENE THERAPY (2001)
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
JY Douillard et al.
LANCET (2000)
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
S Giacchetti et al.
JOURNAL OF CLINICAL ONCOLOGY (2000)