Highly Oriented Nitrogen-doped Carbon Nanotube Integrated Bimetallic Cobalt Copper Organic Framework for Non-enzymatic Electrochemical Glucose and Hydrogen Peroxide Sensor

The hierarchical three-dimensional nitrogen-doped carbon nanotube anchored bimetallic cobalt copper organic framework (NCNT MOF CoCu) is successfully synthesized by the direct growth approach using the high-temperature carbonization of bimetallic cobalt copper organic framework (MOF CoCu-500). The as-prepared NCNT MOF CoCu nanostructure possesses high-level activity for both glucose and hydrogen peroxide (H2O2) sensing molecules. The cyclic voltammetry (CV) and chronoamperometry (CA) studies demonstrate excellent electrocatalytic performance for the oxidation of glucose with a linear range of 0.05 to 2.5 mM, high sensitivity of 1027 mu A mM(-1)cm(-2), and the lowest detection limit of 0.15 mu M. Similarly, the NCNT MOF CoCu nanostructure showed significantly higher H2O2 activity with a linear range of 0.05 to 3.5 mM, high sensitivity of 639.5 mu A mM(-1)cm(-2), and the lowest detection limit of 0.206 mu M. Thanks to its special hierarchical nanoarchitecture, homogeneous nitrogen-doped carbon nanotubes, and highly graphitized carbon, which may be increased the synergistic effect between bimetallic CoCu and NCNT in the organic framework. The potentially effective fabricated sensor was also used as a suitable probe for the detection of glucose and H2O2 in the analysis of the real samples.

Automated summary

The hierarchical three-dimensional nitrogen-doped carbon nanotube anchored bimetallic cobalt copper organic framework (NCNT MOF CoCu) was successfully synthesized by direct growth approach, showing high activity for sensing glucose and hydrogen peroxide molecules. The nanostructure demonstrated excellent catalytic performance for glucose and H2O2 oxidation, making it a potentially effective sensor for real sample analysis.