Journal
DRUG DISCOVERY TODAY
Volume 26, Issue 5, Pages 1284-1292Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2021.01.030
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Gold nanoparticles have been demonstrated to be useful in drug delivery and diagnosis, especially playing important roles in the field of anticancer. Their photothermal and photodynamic properties make them hotspots in therapeutic research, and they have potential anticancer mechanisms in multiple types of cancer.
Gold nanoparticles (AuNPs) have been shown to be useful as carriers of various anticancer drugs as well as diagnosis platforms. In this review, we discuss the synthesis and physiochemical properties of AuNPs. We also highlight the photothermal and photodynamic properties of AuNPs and relevant applications in therapeutic studies. Furthermore, we review the applications of AuNPs in cancer treatment as and their underlying anticancer mechanisms in multiple types of cancer.
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