SINE-B1 Distribution and Chromosome Rearrangements in the South American Proechimys gr. goeldii (Echimyidae, Rodentia)

Proechimys species are remarkable for their extensive chromosome rearrangements, representing a good model to understand genome evolution. Herein, we cytogenetically analyzed 3 different cytotypes of Proechimys gr. goeldii to assess their evolutionary relationship. We also mapped the transposable element SINE-B1 on the chromosomes of P. gr. goeldii in order to investigate its distribution among individuals and evaluate its possible contribution to karyotype remodeling in this species. SINE-B1 showed a dispersed distribution along chromosome arms and was also detected at the pericentromeric regions of some chromosomes, including pair 1 and the sex chromosomes, which are involved in chromosome rearrangements. In addition, we describe a new cytotype for P. gr. goeldii, reinforcing the significant role of gross chromosomal rearrangements during the evolution of the genus. The results of FISH with SINE-B1 suggest that this issue should be more deeply investigated for a better understanding of its role in the mechanisms involved in the wide variety of Proechimys karyotypes.

Automated summary

Proechimys species are known for their extensive chromosome rearrangements, making them a good model to study genome evolution. By analyzing different cytotypes of Proechimys gr. goeldii and mapping the transposable element SINE-B1 on their chromosomes, researchers have identified the significant role of chromosomal rearrangements during the evolution and karyotype remodeling in this species. Further investigations on the distribution and contribution of SINE-B1 in Proechimys karyotypes are needed for a better understanding of the mechanisms involved.