Journal
CURRENT PHARMACEUTICAL DESIGN
Volume 27, Issue 20, Pages 2344-2365Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1381612827666210303141416
Keywords
Breast cancer; omics; genes; diagnosis; biomarkers; therapy
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Funding
- Deanship of Scientific Research at Princess Nourahbint Abdulrahman University through the Fasttrack Research Funding Program
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Breast cancer is described as the most prevalent lifethreatening cancer in women, causing thousands of deaths annually worldwide. This review aims to explore the pathogenesis and treatment options of breast cancer, with the goal of providing effective therapeutic solutions.
Breast cancer has been described as the most prevalent lifethreatening cancer in women. Worldwide, breast cancer causes more than 50,000 deaths annually, accounting for 18% of all women deaths [1-4]. A recent publication has estimated that approximately 80% of women diagnosed with breast cancer each year are aged > 45. In the USA, the health burden of breast cancer is increasing at a drastic rate, with 232,240 newly diagnosed patients and A silent monster, breast cancer, is a challenging medical task for researchers. Breast cancer is a lead-ing cause of death in women with respect to other cancers. A case of breast cancer is diagnosed among women every 19 seconds, and every 74 seconds, a woman dies of breast cancer somewhere in the world. Several risk factors, such as genetic and environmental factors, favor breast cancer development. This review tends to pro-vide deep insights regarding the genetics of breast cancer along with multiple diagnostic and therapeutic ap-proaches as problem-solving negotiators to prevent the progression of breast cancer. This assembled data main-ly aims to discuss omics-based approaches to provide enthralling diagnostic biomarkers and emerging novel therapies to combat breast cancer. This review article intends to pave a new path for the discovery of effective treatment options.
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