Dexmedetomidine as an Adjunct for Regional Anesthetic Nerve Blocks

Purpose of ReviewThis article will review current evidence related to the use of dexmedetomidine as an adjuvant for regional anesthesia.Recent FindingsAdjuvants, frequently used during regional anesthesia, act synergistically with local anesthetics thus enhancing the quality of regional anesthesia while minimizing adverse effects. These adjuvants may be administered via different routes including topical, perineural, neuraxial, and systemic.SummaryRecent studies indicate that dexmedetomidine prolongs the duration of intravenous regional anesthesia, peripheral nerve blocks, and spinal analgesia. Controversy regarding potential neurotoxicity of perineural dexmedetomidine in patients with diabetic neuropathy requires further evaluation.

Automated summary

Recent studies suggest that dexmedetomidine can prolong the duration of intravenous regional anesthesia, peripheral nerve blocks, and spinal analgesia. However, the potential neurotoxicity of perineural dexmedetomidine in diabetic neuropathy patients remains controversial and requires further evaluation.