Journal
CURRENT DRUG TARGETS
Volume 22, Issue 13, Pages 1496-1506Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389450122666210308111159
Keywords
Maslinic acid; cardiovascular diseases; neuroprotection; diabetes; cancer; inflammation; pathogens
Categories
Funding
- Jilin Scientific and Technological Development Program [20190301034NY]
- Changchun City Technology Extension Project of Antibi-otic-free livestock and poultry Production [20200000003]
- Special Project of the Province-University Co-construct-ing Program of Jilin Province [SXGJXX2017-4]
- Jilin Modern Agricultural Technology Demonstration and Extension Project
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Maslinic acid has been found to promote health and resist various diseases. Research has shown its positive effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens, making it a potential nutritional additive and drug candidate.
Since the discovery of (2 alpha,3 beta)-2,3-dihydroxyolean-12-en-28-oic acid, also known as maslinic acid, many studies have examined its biological activity, which has been shown to promote health and resist various diseases. This article focuses on previous research on maslinic acid and mainly reviews its reported effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens. Maslinic acid exerts positive effects on both cell and animal models of disease. Although its mechanism of action has not yet been completely elucidated, maslinic acid is feasible as a nutritional additive and has the potential to be developed as a drug.
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