99mTc-Mebrofenin Hepatobiliary Scintigraphy Combined With SPECT/CT to Assess Liver Function in Heterotopic Segmental Liver Transplantation in the Splenic Fossa

Recent studies have shown that the inclusion of a noninvasive and low-cost functional test such as hepatobiliary scintigraphy is considered more reliable than volume alone to predict posthepatectomy liver failure especially in light of new liver regeneration techniques. We herein reported the unique case of a 40-year-old man who underwent heterotopic liver transplantation of segments 2 and 3 in the splenic fossa after splenectomy for unresectable colorectal liver metastases. Tc-99m-mebrofenin hepatobiliary scintigraphy combined with SPECT/CT was performed after liver transplantation to monitor graft function and regeneration before removal of the native liver.

Automated summary

Recent studies suggest that incorporating a noninvasive and low-cost functional test is more reliable than considering liver volume alone in predicting liver failure posthepatectomy, especially with advancements in liver regeneration techniques. This case report details a unique case of a 40-year-old male who underwent heterotopic liver transplantation, with hepatobiliary scintigraphy performed to monitor graft function and regeneration prior to native liver removal.