Electrical impedance myography: A critical review and outlook

Electrical impedance myography (EIM) technology is finding application in neuromuscular disease research as a tool to assess muscle health. Correlations between EIM outcomes, functional, imaging and histological data have been established in a variety of neuromuscular disorders; however, an analytical discussion of EIM is lacking. This review presents an explanation for clinicians and others who are applying EIM and interpreting impedance outcomes. The background of EIM is presented, including the relation between EIM, volume conduction properties, tissue structure, electrode configuration and conductor volume. Also discussed are technical considerations to guide the reader to critically evaluate EIM and understand its limitations and strengths. (c) 2020 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

Automated summary

Electrical impedance myography (EIM) technology is being used in neuromuscular disease research to assess muscle health. Despite established correlations between EIM outcomes and other data, there is a lack of analytical discussion on EIM, and this review aims to explain EIM and provide technical guidance.