Journal
CELL HOST & MICROBE
Volume 29, Issue 2, Pages 152-154Publisher
CELL PRESS
DOI: 10.1016/j.chom.2021.01.008
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Funding
- Agricultural Genomics Institute at Shenzhen (AGIS), Chinese Academy Agricultural Sciences (CAAS): the Agricultural Science and Technology Innovation Program (ASTIP)
- Guangdong Science and technology foundation [2019ZT08N628]
- National Natural Science Foundation of China [32022006]
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The articles demonstrate that Nucleocytoplasmic large DNA viruses can integrate into host genomes, driving the evolution of eukaryotes through a mechanism of large-scale virus-mediated horizontal gene transfer.
Nucleocytoplasmic large DNA viruses (NCLDVs) are widespread in the biosphere. This issue of Cell Host & Microbe, Nelson et al., and a recent Nature paper, Moniruzzaman et al., show NCLDVs can integrate into host genomes, highlighting a mechanism of large-scale virus-mediated horizontal gene transfer (vHGT) driving eukaryotic evolution.
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