4.8 Review

Genome engineering for crop improvement and future agriculture

Journal

CELL
Volume 184, Issue 6, Pages 1621-1635

Publisher

CELL PRESS
DOI: 10.1016/j.cell.2021.01.005

Keywords

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Funding

  1. Strategic Priority Research Program of the Chinese Academy of Sciences [XDA24020102]
  2. National Natural Science Foundation of China [31788103]
  3. National Key Research and Development Program of China [2016YFD0101804]
  4. Chinese Academy of Sciences [QYZDY-SSW-SMC030]

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Genome editing has the potential to revolutionize plant breeding and address the challenge of feeding a growing population in the face of climate change. Newly developed techniques and strategies offer significant opportunities for plant improvement and crop production, but challenges must be overcome to realize the full potential of this technology.
Feeding the ever-growing population is a major challenge, especially in light of rapidly changing climate conditions. Genome editing is set to revolutionize plant breeding and could help secure the global food supply. Here, I review the development and application of genome editing tools in plants while highlighting newly developed techniques. I describe new plant breeding strategies based on genome editing and discuss their impact on crop production, with an emphasis on recent advancements in genome editing-based plant improvements that could not be achieved by conventional breeding, I also discuss challenges facing genome editing that must be overcome before realizing the full potential of this technology toward future crops and food production.

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