4.8 Article

Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Perspective Rational Cancer Treatment Combinations: An Urgent Clinical Need

Julia Boshuizen et al.

MOLECULAR CELL (2020)

Article Multidisciplinary Sciences

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

Julia Boshuizen et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

David W. Vredevoogd et al.

Article Multidisciplinary Sciences

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis

Max D. Wellenstein et al.

NATURE (2019)

Article Oncology

AXL Is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer

Haley D. Axelrod et al.

MOLECULAR CANCER RESEARCH (2019)

Article Biochemistry & Molecular Biology

Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors

Julia Boshuizen et al.

NATURE MEDICINE (2018)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden

M. D. Hellmann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Multidisciplinary Sciences

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan et al.

NATURE (2018)

Review Immunology

Humanized Mice for the Study of Immuno-Oncology

Philippe De La Rochere et al.

TRENDS IN IMMUNOLOGY (2018)

Article Biochemical Research Methods

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

Roelof J. C. Kluin et al.

BMC BIOINFORMATICS (2018)

Article Multidisciplinary Sciences

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

Rina M. Mbofung et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan et al.

Article Biochemistry & Molecular Biology

Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

Nadeem Riaz et al.

Review Biochemistry & Molecular Biology

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Padmanee Sharma et al.

Article Oncology

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

Weiyi Peng et al.

CANCER DISCOVERY (2016)

Article Dermatology

Immunophenotyping of Stage III Melanoma Reveals Parameters Associated with Patient Prognosis

Nicolas Jacquelot et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2016)

Article Medicine, General & Internal

Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer

Martin Reck et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Itay Tirosh et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

Reprogramming the immunological microenvironment through radiation and targeting Axl

Todd A. Aguilera et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

Stefani Spranger et al.

NATURE (2015)

Article Medicine, General & Internal

Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer

Edward B. Garon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

J. Larkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Cell Biology

Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Philipp Mueller et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Biochemical Research Methods

HTSeq-a Python framework to work with high-throughput sequencing data

Simon Anders et al.

BIOINFORMATICS (2015)

Article Oncology

Genetic Evolution of T-cell Resistance in the Course of Melanoma Progression

Antje Sucker et al.

CLINICAL CANCER RESEARCH (2014)

Article Multidisciplinary Sciences

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

Magdalena Paolino et al.

NATURE (2014)

Article Multidisciplinary Sciences

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Judith Mueller et al.

NATURE COMMUNICATIONS (2014)

Article Oncology

A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors

David J. Konieczkowski et al.

CANCER DISCOVERY (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Review Immunology

Immunogenic Cell Death in Cancer Therapy

Guido Kroemer et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Article Genetics & Heredity

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

Zhenfeng Zhang et al.

NATURE GENETICS (2012)

Article Immunology

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

Surojit Sarkar et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

Article Medicine, General & Internal

Effector memory T cells, early metastasis, and survival in colorectal cancer

F Pagès et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)