Related references
Note: Only part of the references are listed.Regulatory T Cells and Human Disease
Shimon Sakaguchi et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38 (2020)
Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function
Cameron S. Field et al.
CELL METABOLISM (2020)
Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis
Yaqing Zhang et al.
CANCER DISCOVERY (2020)
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
Aaron R. Lim et al.
ELIFE (2020)
Metabolic Adaptations in Cancer Stem Cells
Umesh Prasad Yadav et al.
FRONTIERS IN ONCOLOGY (2020)
FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
Reem Saleh et al.
CANCER LETTERS (2020)
Metabolic regulation of CAR T cell function by the hypoxic microenvironment in solid tumors
Anna Schurich et al.
IMMUNOTHERAPY (2019)
Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?
Yoshihiro Ohue et al.
CANCER SCIENCE (2019)
HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
Jason Miska et al.
CELL REPORTS (2019)
The pan-cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia
Wai Hoong Chang et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2019)
Targeting the tumor microenvironment and T cell metabolism for effective cancer immunotherapy
Helen Carrasco Hope et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2019)
Metabolism and Gut Microbiota in Cancer Immunoediting, CD8/Treg Ratios, Immune Cell Homeostasis, and Cancer (Immuno)Therapy: Concise Review
Irina Kareva
STEM CELLS (2019)
Loss of TET2 and TET3 in regulatory T cells unleashes effector function
Xiaojing Yue et al.
NATURE COMMUNICATIONS (2019)
Treg-mediated acquired resistance to immune checkpoint inhibitors
Reem Saleh et al.
CANCER LETTERS (2019)
The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic review
Sheila A. Fisher et al.
PLOS ONE (2019)
Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
Deblina Raychaudhuri et al.
FRONTIERS IN IMMUNOLOGY (2019)
T Regulatory Cells and Priming the Suppressive Tumor Microenvironment
Christina M. Paluskievicz et al.
FRONTIERS IN IMMUNOLOGY (2019)
TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
Lingyun Xia et al.
CELL METABOLISM (2019)
HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance
Ayako Nagao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Mitochondrial complex III is essential for suppressive function of regulatory T cells
Samuel E. Weinberg et al.
NATURE (2019)
CD4+ CD25+ regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial-mesenchymal transition
Chunying Shi et al.
ONCOTARGETS AND THERAPY (2019)
Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients
Salman M. Toor et al.
FRONTIERS IN IMMUNOLOGY (2019)
T-Regulatory Cells In Tumor Progression And Therapy
Amit Verma et al.
CANCER MANAGEMENT AND RESEARCH (2019)
γδ T cells in cancer: a small population of lymphocytes with big implications
Mathilde Raverdeau et al.
CLINICAL & TRANSLATIONAL IMMUNOLOGY (2019)
Regulatory T cells mediate resistance to radiotherapy in head and neck squamous cell carcinoma.
Ayman Oweida et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues
Margaret M. Lowe et al.
JCI INSIGHT (2019)
Concise Review: Metabolism and Gut Microbiota in Cancer Immunoediting, CD8/Treg Ratios, Immune Cell Homeostasis, and Cancer (Immuno)Therapy
Irina Kareva
STEM CELLS (2019)
Reprogramming of Th1 cells into regulatory T cells through rewiring of the metabolic status
Mitsuhiro Kanamori et al.
INTERNATIONAL IMMUNOLOGY (2018)
mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells
Im-Hong Sun et al.
JOURNAL OF IMMUNOLOGY (2018)
Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth
Ilenia Pacella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
mTOR coordinates transcriptional programs and mitochondrial metabolism of activated T-reg subsets to protect tissue homeostasis
Nicole M. Chapman et al.
NATURE COMMUNICATIONS (2018)
The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations
Roddy S. O'Connor et al.
SCIENTIFIC REPORTS (2018)
RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells
Angelamaria Rizzo et al.
CANCER IMMUNOLOGY RESEARCH (2018)
IL35 Hinders Endogenous Antitumor T-cell Immunity and Responsiveness to Immunotherapy in Pancreatic Cancer
Bhalchandra Mirlekar et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Effects of tumor metabolic microenvironment on regulatory T cells
Yi-an Wang et al.
MOLECULAR CANCER (2018)
Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types
Angela M. Magnuson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8(+) T cells in the tumor microenvironment
Yasuko Tada et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
Madhav Kishore et al.
IMMUNITY (2017)
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
Youdong Pan et al.
NATURE (2017)
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1
Nanhai He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment
Azharuddin Sajid Syed Khaja et al.
ONCOTARGET (2017)
Fatty Acid Uptake in T Cell Subsets Using a Quantum Dot Fatty Acid Conjugate
Megan E. Muroski et al.
SCIENTIFIC REPORTS (2017)
Distinct Blood and Visceral Adipose Tissue Regulatory T Cell and Innate Lymphocyte Profiles Characterize Obesity and Colorectal Cancer
Gloria Donninelli et al.
FRONTIERS IN IMMUNOLOGY (2017)
Intratumoral FoxP3+Helios+ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
Azharuddin Sajid Syed Khaja et al.
FRONTIERS IN IMMUNOLOGY (2017)
Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance
Eirini Nikolouli et al.
FRONTIERS IN IMMUNOLOGY (2017)
Impact of Metabolism in on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment
Soumaya Kouidhi et al.
FRONTIERS IN IMMUNOLOGY (2017)
The Specific Roles of Vitamins in the Regulation of Immunosurveillance and Maintenance of Immunologic Homeostasis in the Gut
Koji Hosomi et al.
IMMUNE NETWORK (2017)
IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+ T cells
Lea M. Feldhoff et al.
SCIENTIFIC REPORTS (2017)
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor
Tomasz Maj et al.
NATURE IMMUNOLOGY (2017)
Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
Ying Zhang et al.
CANCER CELL (2017)
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma
Peter J. Siska et al.
JCI INSIGHT (2017)
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
Alessia Angelin et al.
CELL METABOLISM (2017)
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity
Abigail E. Overacre-Delgoffe et al.
CELL (2017)
Regulation of PD-L1: a novel role of pro-survival signalling in cancer
J. Chen et al.
ANNALS OF ONCOLOGY (2016)
CTLA-4 and PD-1 Pathways Similarities, Differences, and Implications of Their Inhibition
Elizabeth I. Buchbinder et al.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2016)
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
David Clever et al.
CELL (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
Impact of the physical microenvironment on tumor progression and metastasis
Fabian Spill et al.
CURRENT OPINION IN BIOTECHNOLOGY (2016)
Role of TET enzymes in DNA methylation, development, and cancer
Kasper Dindler Rasmussen et al.
GENES & DEVELOPMENT (2016)
Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer
George Plitas et al.
IMMUNITY (2016)
PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma
Melanie Ruf et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Control of Foxp3 stability through modulation of TET activity
Xiaojing Yue et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Vitamin C Facilitates Demethylation of the Foxp3 Enhancer in a Tet-Dependent Manner
Varun Sasidharan Nair et al.
JOURNAL OF IMMUNOLOGY (2016)
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
Valerie A. Gerriets et al.
NATURE IMMUNOLOGY (2016)
Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers
Takuro Saito et al.
NATURE MEDICINE (2016)
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
Robert U. Svensson et al.
NATURE MEDICINE (2016)
IDO1 involvement in mTOR pathway: A molecular mechanism of resistance to mTOR targeting in medulloblastoma
Valentina Folgiero et al.
ONCOTARGET (2016)
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma
Mira A. Patel et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2016)
T cell receptor signalling in the control of regulatory T cell differentiation and function
Ming O. Li et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting
Belal Chaudhary et al.
VACCINES (2016)
E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity
Jee H. Lee et al.
IMMUNITY (2015)
Hypoxic culture conditions enhance the generation of regulatory T cells
Thi My Anh Neildez-Nguyen et al.
IMMUNOLOGY (2015)
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
Sharad Shrestha et al.
NATURE IMMUNOLOGY (2015)
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
Alexandria Huynh et al.
NATURE IMMUNOLOGY (2015)
Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis
Bin Shang et al.
SCIENTIFIC REPORTS (2015)
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
Madhav D. Sharma et al.
SCIENCE ADVANCES (2015)
Foxp3-mediated inhibition of Akt inhibits Glut1 (glucose transporter 1) expression in human T regulatory cells
Samik Basu et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
Neuropilin 1: function and therapeutic potential in cancer
Belal Chaudhary et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth
Yuan Yin et al.
CELL RESEARCH (2014)
Regulatory T cells in cancer immunotherapy
Hiroyoshi Nishikawa et al.
CURRENT OPINION IN IMMUNOLOGY (2014)
Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
Nagendra Singh et al.
IMMUNITY (2014)
Indoleamine 2,3-Dioxygenase 1 (IDO1) Is Up-Regulated in Thyroid Carcinoma and Drives the Development of an Immunosuppressant Tumor Microenvironment
Sonia Moretti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction
Christian A. Bauer et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
Ovijit Chaudhuri et al.
NATURE MATERIALS (2014)
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
Luciana Berod et al.
NATURE MEDICINE (2014)
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions
Ling Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer
Jie-Yao Li et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2014)
Human gamma delta T regulatory cells in cancer: fact or fiction?
Daniela Wesch et al.
FRONTIERS IN IMMUNOLOGY (2014)
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih-Hao Chang et al.
CELL (2013)
Effects of Adjuvant Chemoradiotherapy on the Frequency and Function of Regulatory T Cells in Patients with Head and Neck Cancer
Patrick J. Schuler et al.
CLINICAL CANCER RESEARCH (2013)
TGF-beta signaling and epithelial-mesenchymal transition in cancer progression
Yoko Katsuno et al.
CURRENT OPINION IN ONCOLOGY (2013)
Hypothermic microenvironment plays a key role in tumor immune subversion
Gangjun Du et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
Butyrophilin 3A1 Plays an Essential Role in Prenyl Pyrophosphate Stimulation of Human V gamma 2V delta 2 T Cells
Hong Wang et al.
JOURNAL OF IMMUNOLOGY (2013)
Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis
Greg M. Delgoffe et al.
NATURE (2013)
mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
Hu Zeng et al.
NATURE (2013)
Intratumor Hypoxia Promotes Immune Tolerance by Inducing Regulatory T Cells via TGF-β1 in Gastric Cancer
Bin Deng et al.
PLOS ONE (2013)
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Fabienne Guillaumond et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Neuropilin-1 in transplantation tolerance
Mauricio Campos-Mora et al.
FRONTIERS IN IMMUNOLOGY (2013)
1,25-Dihyroxyvitamin D3 Promotes FOXP3 Expression via Binding to Vitamin D Response Elements in Its Conserved Noncoding Sequence Region
Seong Wook Kang et al.
JOURNAL OF IMMUNOLOGY (2012)
Tumor-Infiltrating γδ T Lymphocytes Predict Clinical Outcome in Human Breast Cancer
Chunling Ma et al.
JOURNAL OF IMMUNOLOGY (2012)
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Eric T. Clambey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation
Nikolaos Patsoukis et al.
SCIENCE SIGNALING (2012)
Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination
Taylor H. Schreiber et al.
ONCOIMMUNOLOGY (2012)
The immune contexture in human tumours: impact on clinical outcome
Wolf Herman Fridman et al.
NATURE REVIEWS CANCER (2012)
Cancer: More of Polygenic Disease and Less of Multiple Mutations? A Quantitative Viewpoint
Anders Bredberg
CANCER (2011)
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
Eric V. Dang et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release
Kristina Goetze et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
Lewis Z. Shi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer
Ilona Kryczek et al.
JOURNAL OF IMMUNOLOGY (2011)
Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
Ryan D. Michalek et al.
JOURNAL OF IMMUNOLOGY (2011)
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Christiane A. Opitz et al.
NATURE (2011)
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
Wei Tan et al.
NATURE (2011)
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
Andrea Facciabene et al.
NATURE (2011)
All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus
Ling Lu et al.
PLOS ONE (2011)
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation
Ryan D. Michalek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors
Ursula Schenk et al.
SCIENCE SIGNALING (2011)
An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness
Claudio Procaccini et al.
IMMUNITY (2010)
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
Rachel A. Gottschalk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Low-dose Cyclophosphamide Treatment Impairs Regulatory T Cells and Unmasks AFP-specific CD4+ T-cell Responses in Patients With Advanced HCC
Tim F. Greten et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)
Marta Szajnik et al.
PLOS ONE (2010)
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
Nam Trung Nguyen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
Madhav D. Sharma et al.
BLOOD (2009)
Gamma irradiation alters the phenotype and function of CD4+CD25+ regulatory T cells
Mengde Cao et al.
CELL BIOLOGY INTERNATIONAL (2009)
Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity
Shomyseh Sanjabi et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?
Maria A. Curotto de Lafaille et al.
IMMUNITY (2009)
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
Makoto Miyara et al.
IMMUNITY (2009)
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
Loise M. Francisco et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3
Louisa E. Jeffery et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: TGF-β1 and IL-15 Induce FOXP3+ γδ Regulatory T Cells in the Presence of Antigen Stimulation
Rita Casetti et al.
JOURNAL OF IMMUNOLOGY (2009)
IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells
Babak Baban et al.
JOURNAL OF IMMUNOLOGY (2009)
Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+regulatory T cells
Paul L. Bollyky et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Role and regulation of prolyl hydroxylase domain proteins
G-H Fong et al.
CELL DEATH AND DIFFERENTIATION (2008)
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: Its association with disease progression and survival
Kazuhiko Ino et al.
CLINICAL CANCER RESEARCH (2008)
Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α
Jeremy Ben-Shoshan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells
Jonathan A. Hill et al.
IMMUNITY (2008)
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
Sokol Haxhinasto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
The tumor microenvironment and its role in promoting tumor growth
T. L. Whiteside
ONCOGENE (2008)
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
Stephan Sauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A(2A) receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
Paul E. Zarek et al.
BLOOD (2008)
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
Justin T. Jordan et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
Drug resistance and the solid tumor microenvironment
Olivier Tredan et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
Xuefang Cao et al.
IMMUNITY (2007)
Transforming growth factor-β and the immune response:: Implications for anticancer therapy
Stephen H. Wrzesinski et al.
CLINICAL CANCER RESEARCH (2007)
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells:: hydrolysis of extracellular ATP and immune suppression
Giovanna Borsellino et al.
BLOOD (2007)
Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma
Shuang Wei et al.
CANCER RESEARCH (2007)
Tumor-infiltrating γδ T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway
Guangyong Peng et al.
IMMUNITY (2007)
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
Daniel Mucida et al.
SCIENCE (2007)
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
Silvia Deaglio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Expression of indoleamine 2, 3-dioxygenase and the recruitment of Foxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer
Takafumi Nakamura et al.
CANCER SCIENCE (2007)
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
David H. Munn et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Altered activation of AKT is required for the suppressive function of human CD4+ CD25+ T regulatory cells
Natasha K. Crellin et al.
BLOOD (2007)
IL-2 is essential for TGF-β to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells
Song Guo Zheng et al.
JOURNAL OF IMMUNOLOGY (2007)
Perspectives of gamma delta T cells in tumor immunology
Dieter Kabelitz et al.
CANCER RESEARCH (2007)
Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis.
Sachin Gupta et al.
ACTA ONCOLOGICA (2007)
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
Gaynor J. Bates et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
Francesca Fallarino et al.
JOURNAL OF IMMUNOLOGY (2006)
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer:: Effect on tumor-infiltrating T cells
G Brandacher et al.
CLINICAL CANCER RESEARCH (2006)
Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
G Zhou et al.
BLOOD (2006)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
DH Munn et al.
IMMUNITY (2005)
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
TJ Curiel et al.
NATURE MEDICINE (2004)
Pellagra: Dermatitis, dementia, and diarrhea
J Hegyi et al.
INTERNATIONAL JOURNAL OF DERMATOLOGY (2004)
Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells
HJ Gober et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
T cell apoptosis by tryptophan catabolism
I Fallarino et al.
CELL DEATH AND DIFFERENTIATION (2002)
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
UK Liyanage et al.
JOURNAL OF IMMUNOLOGY (2002)
Lactate stimulates fibroblast expression of hyaluronan and CD44: The Warburg effect revisited
R Stern et al.
EXPERIMENTAL CELL RESEARCH (2002)
Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4+ T-regulatory cells and systemic collapse of antitumour immunity
N Seo et al.
IMMUNOLOGY (2001)
Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
T Takahashi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Share Paper
