Journal
CANCER CELL
Volume 39, Issue 3, Pages 304-306Publisher
CELL PRESS
DOI: 10.1016/j.ccell.2021.02.012
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Funding
- NIH NINDS [R35 NS105109-01, P30 CA08748]
- National Brain Tumor Society Defeat GBM initiative
- Emerson Collective Cancer Fund
- Cycle for Survival
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A study published in Nature in 2020 challenges the notion of the brain as an immune-privileged organ by discovering functional lymphatic vessels in the meninges. These meningeal lymphatics are found to play an important role in sensing brain tumor antigens.
The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens.
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