Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 195, Issue 1, Pages 15-24Publisher
WILEY
DOI: 10.1111/bjh.17404
Keywords
lymphoma; lymphoproliferative disease; non‐ Hodgkin lymphoma; lymphoid malignancies
Categories
Ask authors/readers for more resources
Grade 3B follicular lymphoma is rare and often excluded from clinical trials, leading to conflicting data on diagnosis, outcomes, therapy choices, and imaging role. New research is exploring unique genetic characteristics, PET imaging features, therapy choices, and outcomes in the current era, highlighting the importance of characterization and treatment of G3B FL.
Grade 3B follicular lymphoma (G3B FL) is rare, accounting for only 5-10% of FLs. Not only has it been routinely excluded from clinical trials, but data published on diagnosis, outcomes, choice of therapies and role of imaging are conflicting. With the advent of increasingly diverse treatment options for low-grade (G1-3A) FL, and the molecular subcategorisation of high-grade B-cell lymphomas, characterisation and treatment of G3B FL is ever more important as extrapolation of data becomes more difficult. New data have emerged exploring unique genetic characteristics, specific features on positron emission tomography imaging, choice of therapy, and outcomes of G3B FL in the current era. The present review will summarise and appraise these new data, and offer recommendations based on current evidence.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available