Journal
ELECTROPHORESIS
Volume 37, Issue 5-6, Pages 786-789Publisher
WILEY
DOI: 10.1002/elps.201500535
Keywords
Carcinoembryonic antigen; Microfluidics; SERS; Magnetic nanoparticles
Funding
- National Key Scientific Instrument and Equipment Development Project, China [2011YQ03012404]
- State Project for Essential Drug Research and Development, China [2013ZX09507005001]
- National Natural Science Foundation, China [81171486]
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Carcinoembryonic antigen (CEA) is a wide-spectrum biomarker. Clinically, we generally use serum sample to detect CEA, which needs to be centrifuged to pretreat the raw blood sample. In this study, we realized direct CEA detection in raw blood samples exploiting microfluidics. The LOD was as low as 10(-12) M.
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