Related references
Note: Only part of the references are listed.Synthesis, evaluation and docking of novel pyrazolo pyrimidines as potent p38α MAP kinase inhibitors with improved anti-inflammatory, ulcerogenic and TNF-α inhibitory properties
Kanagasabai Somakala et al.
BIOORGANIC CHEMISTRY (2019)
Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors
Fabian Heider et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies
Mohammed El-Gamal et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer's disease models
Yehong Du et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)
Synthesis, anti-inflammatory, p38α MAP kinase inhibitory activities and molecular docking studies of quinoxaline derivatives containing triazole moiety
Sana Tariq et al.
BIOORGANIC CHEMISTRY (2018)
Cirsimarin, a flavone glucoside from the aerial part of Cirsium japonicum var. ussuriense (Regel) Kitam. ex Ohwi, suppresses the JAK/STAT and IRF-3 signaling pathway in LPS-stimulated RAW 264.7 macrophages
Hee-Soo Han et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2018)
被撤回的出版物: UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer (Retracted article. See vol. 26, pg. 1777, 2020)
Rabia A. Gilani et al.
CLINICAL CANCER RESEARCH (2016)
Synthesis and p38 Inhibitory Activity of Some Novel Substituted N,N′-Diarylurea Derivatives
Dianxi Zhu et al.
MOLECULES (2016)
In vitro anti-osteoclastogenic activity of p38 inhibitor doramapimod via inhibiting migration of pre-osteoclasts and NFATc1 activity
Seong-Hee Moon et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2015)
Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial
L. Kristin Newby et al.
LANCET (2014)
Molecular basis of MAP kinase regulation
Wolfgang Peti et al.
PROTEIN SCIENCE (2013)
Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes
Carlos Guijas et al.
JOURNAL OF LIPID RESEARCH (2012)
RG7204 (PLX4032), a Selective BRAFV600E Inhibitor, Displays Potent Antitumor Activity in Preclinical Melanoma Models
Hong Yang et al.
CANCER RESEARCH (2010)
Comparative renal excretion of VX-702, a novel p38 MAPK inhibitor, and methotrexate in the perfused rat kidney model
Mitalee Tamhane et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2010)
Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases
Chunjian Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Evaluation of the Efficacy and Safety of Pamapimod, a p38 MAP Kinase Inhibitor, in a Double-Blind, Methotrexate-Controlled Study of Patients With Active Rheumatoid Arthritis
Stanley B. Cohen et al.
ARTHRITIS AND RHEUMATISM (2009)
Development of a Fluorescent-Tagged Kinase Assay System for the Detection and Characterization of Allosteric Kinase Inhibitors
Jeffrey R. Simard et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
SD0006: A Potent, Selective and Orally Available Inhibitor of p38 Kinase
Barry L. Burnette et al.
PHARMACOLOGY (2009)
Signal integration by JNK and p38 MAPK pathways in cancer development
Erwin F. Wagner et al.
NATURE REVIEWS CANCER (2009)
How Antirheumatic Drugs Protect Joints From Damage in Rheumatoid Arthritis
Georg Schett et al.
ARTHRITIS AND RHEUMATISM (2008)
Benzothiazole based inhibitors of p38α MAP kinase
Chunjian Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
A potent and selective p38 inhibitor protects against bone damage in murine collagen-induced arthritis:: a comparison with neutralization of mouse TNFα
K. Mihara et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Design, synthesis, and biological evaluation of novel tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: Focus on optimized interactions with the enzyme's surface-exposed front region
Stefan A. Laufer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
MAP kinase signalling pathways in cancer
A. S. Dhillon et al.
ONCOGENE (2007)
A sensitive direct ELISA for detection of prostaglandin E2
Nuntana Aroonrerk et al.
JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY (2007)
Theoretical and experimental design of atypical kinase inhibitors: Application to p38 MAP kinase
KF McClure et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Chemokine production and E-selectin expression in activated endothelial cells are inhibited by p38 MAPK (mitogen activated protein kinase) inhibitor RWJ 67657
J Westra et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2005)
Phosphodiesterase inhibitors stimulate osteoclast formation via TRANCE/RANKL expression in osteoblasts: possible involvement of ERK and p38 MAPK pathways
M Takami et al.
FEBS LETTERS (2005)
The biology of p38 kinase: A central role in inflammation
GL Schieven
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor β-induced Smad signaling in human ovarian cancer cells
YX Fu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Novel substituted quinoxaline 1,4-dioxides with in vitro antimycobacterial and anticandida activity
A Carta et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2002)
Lipopolysaccharide-induced expression of interferon-β mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages
AT Jacobs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers
JW Fijen et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2001)
Differential effects of SB 242235, a selective p38 mitogen-activated protein kinase inhibitor, on IL-1 treated bovine and human cartilage/chondrocyte cultures
AM Badger et al.
OSTEOARTHRITIS AND CARTILAGE (2000)
Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6
W Vanden Berghe et al.
BIOCHEMICAL PHARMACOLOGY (2000)
p38 MAP kinases: beyond the stress response
AR Nebreda et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Serum-induced monocyte differentiation and monocyte chemotaxis are regulated by the p38 MAP kinase signal transduction pathway
JM Ayala et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2000)
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms
H Enslen et al.
EMBO JOURNAL (2000)
Symplectic algorithm for constant-pressure molecular dynamics using a Nose-Poincare thermostat
JB Sturgeon et al.
JOURNAL OF CHEMICAL PHYSICS (2000)
The p38 signal transduction pathway - Activation and function
K Ono et al.
CELLULAR SIGNALLING (2000)