4.7 Review

Imaging genomics for accurate diagnosis and treatment of tumors: A cutting edge overview

Journal

BIOMEDICINE & PHARMACOTHERAPY
Volume 135, Issue -, Pages -

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2020.111173

Keywords

Cancer; Imaging genomics; Radiogenomics; Magnetic resonance; Computed tomography; Artificial intelligence

Funding

  1. Guangdong Science and Technology Department [2016B030309002, 2019B090905011]
  2. Fund of Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang) [ZJW-2019-007]
  3. Science and Technology Program of Zhanjiang [2017A06012]
  4. Public Service Platform of South China Sea for R&D Marine Biomedicine Resources [GDMUK201808]

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Imaging genomics plays a crucial role in understanding tumor characteristics and researching tumor treatment, particularly in aspects such as tumor screening, diagnosis, and prognosis evaluation.
Imaging genomics refers to the establishment of the connection between invasive gene expression features and non-invasive imaging features. Tumor imaging genomics can not only understand the macroscopic phenotype of tumor, but also can deeply analyze the cellular and molecular characteristics of tumor tissue. In recent years, tumor imaging genomics has been a key in the field of medicine. The incidence of cancer in China has increased significantly, which is the main reason of disease death of urban residents. With the rapid development of imaging medicine, depending on imaging genomics, many experts have made remarkable achievements in tumor screening and diagnosis, prognosis evaluation, new treatment targets and understanding of tumor biological mechanism. This review analyzes the relationship between tumor radiology and gene expression, which provides a favorable direction for clinical staging, prognosis evaluation and accurate treatment of tumors.

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