Journal
ARTIFICIAL ORGANS
Volume 45, Issue 7, Pages 779-783Publisher
WILEY
DOI: 10.1111/aor.13929
Keywords
dialysate; dialysis fluid; dysnatremia; end‐ stage kidney disease; hemodialysis; sodium
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The proposed new dialysis fluid delivery system allows for a wide range of dialysis fluid sodium concentrations without affecting other crucial solutes, by adjusting product water and sodium chloride concentrate streams while keeping the acid and sodium bicarbonate concentrate ingredients constant.
We propose a new 45X, four-stream, triple-concentrate, bicarbonate-based dialysis fluid delivery system, allowing a wide range of dialysis fluid sodium concentrations\\ (DFNa) without affecting the concentrations of other crucial solutes. The four streams consist of product water (W), and concentrates with sodium chloride (S), acid (A), and sodium bicarbonate (B). An adjustment in the DFNa in this new system requires changes only in the W and S concentrate streams. The ingredients in A and B concentrates do not change.
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