Related references
Note: Only part of the references are listed.Full recovery of the Alzheimer's disease phenotype by gain of function of vacuolar protein sorting 35
Jian-Guo Li et al.
MOLECULAR PSYCHIATRY (2020)
Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein
Wileidy Gomez et al.
AGING-US (2020)
Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons
Fu-Lei Tang et al.
CELL DEATH AND DIFFERENTIATION (2020)
A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles
Jian-Guo Li et al.
MOLECULAR NEURODEGENERATION (2020)
Dysregulation of the Retromer Complex System in Down Syndrome
Mary Elizabeth Curtis et al.
ANNALS OF NEUROLOGY (2020)
Retro Is Cool: Structure of the Versatile Retromer Complex
Leonora Martinez-Nunez et al.
STRUCTURE (2020)
Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings
Selene Lomoio et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Lysosome trafficking and signaling in health and neurodegenerative diseases
Pearl P. Y. Lie et al.
NEUROBIOLOGY OF DISEASE (2019)
Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)
Ying Jiang et al.
JOURNAL OF NEUROSCIENCE (2019)
VPS29, a tweak tool of endosomal recycling
Soledad Banos-Mateos et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
Enhanced generation of intraluminal vesicles in neuronal late endosomes in the brain of a Down syndrome mouse model with endosomal dysfunction
Pasquale D'Acunzo et al.
DEVELOPMENTAL NEUROBIOLOGY (2019)
Understanding phosphoinositides: rare, dynamic, and essential membrane phospholipids
Eamonn J. Dickson et al.
BIOCHEMICAL JOURNAL (2019)
Retromer has a selective function in cargo sorting via endosome transport carriers
Yi Cui et al.
JOURNAL OF CELL BIOLOGY (2019)
Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years
Rosalyn Hithersay et al.
JAMA NEUROLOGY (2019)
microRNA 155 up regulation in the CNS is strongly correlated to Down's syndrome dementia
Esmerina Tili et al.
ANNALS OF DIAGNOSTIC PATHOLOGY (2018)
Trisomy of human chromosome 21 enhances amyloid-beta deposition independently of an extra copy of APP
Frances K. Wiseman et al.
BRAIN (2018)
Rab GTPases and Membrane Trafficking in Neurodegeneration
Ferdi Ridvan Kiral et al.
CURRENT BIOLOGY (2018)
Exosomal biomarkers in Down syndrome and Alzheimer's disease
Eric D. Hamlett et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Endosomal receptor trafficking: Retromer and beyond
Jing Wang et al.
TRAFFIC (2018)
The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases
Hongfeng Zhang et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein
Jessica E. Young et al.
STEM CELL REPORTS (2018)
Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A
Thu Lan Nguyen et al.
DISEASE MODELS & MECHANISMS (2018)
Endosomal Retrieval of Cargo: Retromer Is Not Alone
Kerrie E. McNally et al.
TRENDS IN CELL BIOLOGY (2018)
The Endolysosomal System and Proteostasis: From Development to Degeneration
Bettina Winckler et al.
JOURNAL OF NEUROSCIENCE (2018)
Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease
Ralph A. Nixon
FASEB JOURNAL (2017)
Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport
Arunas Kvainickas et al.
JOURNAL OF CELL BIOLOGY (2017)
Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling
Kerrie E. McNally et al.
NATURE CELL BIOLOGY (2017)
The retromer complex system in a transgenic mouse model of AD: influence of age
Jin Chu et al.
NEUROBIOLOGY OF AGING (2017)
The Retromer Supports AMPA Receptor Trafficking During LTP
Paul Temkin et al.
NEURON (2017)
Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease
Scott A. Small et al.
TRENDS IN NEUROSCIENCES (2017)
VPS35, the Retromer Complex and Parkinson's Disease
Erin T. Williams et al.
JOURNAL OF PARKINSONS DISEASE (2017)
Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities
Sebastien A. Gauthier et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Molecular definitions of autophagy and related processes
Lorenzo Galluzzi et al.
EMBO JOURNAL (2017)
Intersectin scaffold proteins and their role in cell signaling and endocytosis
Erika Herrero-Garcia et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
SNX27, a Protein Involved in Down Syndrome, Regulates GPR17 Trafficking and Oligodendrocyte Differentiation
Veronica Meraviglia et al.
GLIA (2016)
Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination
Jose Luis Olmos-Serrano et al.
NEURON (2016)
Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome
Jamie R. K. Marland et al.
PLOS ONE (2016)
COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A
Christine A. Phillips-Krawczak et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation
Yun Tian et al.
MOLECULAR BRAIN (2015)
The Use of Pharmacological Retromer Chaperones in Alzheimer's Disease and other Endosomal-related Disorders
Diego E. Berman et al.
NEUROTHERAPEUTICS (2015)
Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain
Marzia Perluigi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
A patient with partial trisomy 21 and 7q deletion expresses mild Down syndrome phenotype
I. Papoulidis et al.
GENE (2014)
Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson's disease mutant of Leucine-rich repeat kinase 2 (LRRK2)
Radek Linhart et al.
MOLECULAR NEURODEGENERATION (2014)
Pharmacological chaperones stabilize retromer to limit APP processing
Vincent J. Mecozzi et al.
NATURE CHEMICAL BIOLOGY (2014)
Clathrin-Independent Pathways of Endocytosis
Satyajit Mayor et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Emerging Roles for Intersectin (ITSN) in Regulating Signaling and Disease Pathways
Michael P. Hunter et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome
Xin Wang et al.
NATURE MEDICINE (2013)
RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson's Disease Risk
David A. MacLeod et al.
NEURON (2013)
Trisomy for Synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes
Jack-Christophe Cossec et al.
HUMAN MOLECULAR GENETICS (2012)
The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space
Rocio Perez-Gonzalez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network
Regina Wai-Yan Choy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
VPS35 Mutations in Parkinson Disease
Carles Vilarino-Gueell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Endosome maturation
Jatta Huotari et al.
EMBO JOURNAL (2011)
VPS35 haploinsufficiency increases Alzheimer's disease neuropathology
Lei Wen et al.
JOURNAL OF CELL BIOLOGY (2011)
Endosomal sorting of AMPA receptors in hippocampal neurons
Jonathan G. Hanley
BIOCHEMICAL SOCIETY TRANSACTIONS (2010)
Updated National Birth Prevalence Estimates for Selected Birth Defects in the United States, 2004-2006
Samantha E. Parker et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2010)
INTERSECTINg Pathways in Cell Biology
John P. O'Bryan
SCIENCE SIGNALING (2010)
Down syndrome fibroblast model of Alzheimer-related endosome pathology - Accelerated endocytosis promotes late endocytic defects
Anne M. Cataldo et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities
Yong Yu et al.
HUMAN MOLECULAR GENETICS (2008)
ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1
Wei Wang et al.
TRAFFIC (2008)
Caenorhabditis elegans intersectin:: A synaptic protein regulating neurotransmission
Simon Rose et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Gene expression profiling in the adult Down syndrome brain
H. E. Lockstone et al.
GENOMICS (2007)
Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain
A. Nistor et al.
NEUROBIOLOGY OF AGING (2007)
Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome
Joseph. H. Lee et al.
NEUROSCIENCE LETTERS (2007)
Rab35 regulates an endocytic recycling pathwav essential for the terminal steps of cytokinesis
Ilektra Kouranti et al.
CURRENT BIOLOGY (2006)
Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis
TW Koh et al.
NEURON (2004)
Pharmacological chaperones:: potential treatment for conformational diseases
V Bernier et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2004)
Beta 1 integrin activation mediates adhesive differences between trisomy 21 and non-trisomic fibroblasts on type VI collagen
IN Jongewaard et al.
AMERICAN JOURNAL OF MEDICAL GENETICS (2002)
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
JD Cooper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Share Paper
