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Nonviral delivery of self-amplifying RNA vaccines
Andrew J. Geall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Developing mRNA-vaccine technologies
Thomas Schlake et al.
RNA BIOLOGY (2012)
Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species
Stefano Colloca et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Indicators of therapeutic effect in FIT-06, a Phase II trial of a DNA vaccine, GTU®-Multi-HIVB, in untreated HIV-1 infected subjects
Eftyhia Vardas et al.
VACCINE (2012)
Advax™, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses
Yoshikazu Honda-Okubo et al.
VACCINE (2012)
Vaccines: From Empirical Development to Rational Design
Christine Rueckert et al.
PLOS PATHOGENS (2012)
Viral Vector-Based Therapeutic Cancer Vaccines
Cecilia Larocca et al.
CANCER JOURNAL (2011)
Electroporation delivery of DNA vaccines: prospects for success
Niranjan Y. Sardesai et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial
Julie E. Ledgerwood et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Intranasal DNA Vaccination Induces Potent Mucosal and Systemic Immune Responses and Cross-protective Immunity Against Influenza Viruses
Lea Torrieri-Dramard et al.
MOLECULAR THERAPY (2011)
In Vivo Electroporation Enhances the Immunogenicity of an HIV-1 DNA Vaccine Candidate in Healthy Volunteers
Sandhya Vasan et al.
PLOS ONE (2011)
The PEDVAC trial: Preliminary data from the first therapeutic DNA vaccination in HIV-infected children
Paolo Palma et al.
VACCINE (2011)
International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations
Dan H. Barouch et al.
VACCINE (2011)
Evaluation of a prototype dengue-1 DNA vaccine in a Phase 1 clinical trial
Charmagne G. Beckett et al.
VACCINE (2011)
Recent trends in vaccine delivery systems: A review
C. H. Saroja et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2011)
Intranasal vaccination with messenger RNA as a new approach in gene therapy: Use against tuberculosis
Julio C. C. Lorenzi et al.
BMC BIOTECHNOLOGY (2010)
Bioadhesive chitosan nanoparticles: Preparation and characterization
Anitha R. Dudhani et al.
CARBOHYDRATE POLYMERS (2010)
Progress and prospects: nuclear import of nonviral vectors
A. P. Lam et al.
GENE THERAPY (2010)
Vaccine Adjuvants: Putting Innate Immunity to Work
Robert L. Coffman et al.
IMMUNITY (2010)
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Acts as a Dominant Immunogen Revealed by a Clustering Region of Novel Functionally and Structurally Defined Cytotoxic T-Lymphocyte Epitopes
Jun Liu et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Subcutaneous and visceral adipose tissue: structural and functional differences
M. Mohsen Ibrahim
OBESITY REVIEWS (2010)
Preferential Amplification of CD8 Effector-T Cells after Transcutaneous Application of an Inactivated Influenza Vaccine: A Randomized Phase I Trial
Behazine Combadiere et al.
PLOS ONE (2010)
Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients
Zhiliang Cao et al.
VIROLOGY JOURNAL (2010)
Coronavirus Genomics and Bioinformatics Analysis
Patrick C. Y. Woo et al.
VIRUSES-BASEL (2010)
The spike protein of SARS-CoV - a target for vaccine and therapeutic development
Lanying Du et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Original Encounter with Antigen Determines Antigen-Presenting Cell Imprinting of the Quality of the Immune Response in Mice
Valerie Abadie et al.
PLOS ONE (2009)
Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen
Jian Yan et al.
VACCINE (2009)
Pulmonary Eosinophilia Is Attenuated by Early Responding CD8+ Memory T Cells in a Murine Model of RSV Vaccine-Enhanced Disease
Whitney W. Stevens et al.
VIRAL IMMUNOLOGY (2009)
Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
A. M. M. Sadeghi et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2008)
Overcoming T-cell-mediated immunopathology to achieve safe respiratory syncytial virus vaccination
Elaine M. Castilow et al.
FUTURE VIROLOGY (2008)
Transcutaneous anti-influenza vaccination promotes both CD4 and CD8 T cell immune responses in humans
Annika Vogt et al.
JOURNAL OF IMMUNOLOGY (2008)
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
Susan P. Buchbinder et al.
LANCET (2008)
Mechanisms of disease: Systemic lupus erythematosus
Anisur Rahman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques
Jian Yan et al.
VACCINE (2008)
Intradermal vaccine delivery: Will new delivery systems transform vaccine administration?
Paul Henri Lambert et al.
VACCINE (2008)
A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial
Julie E. Martin et al.
VACCINE (2008)
Replicating and non-replicating viral vectors for vaccine development
Marjorie Robert-Guroff
CURRENT OPINION IN BIOTECHNOLOGY (2007)
Preservation of DNA
Thomas J. Anchordoquy et al.
CELL PRESERVATION TECHNOLOGY (2007)
Long-term storage of DNA-free RNA for use in vaccine studies
Kathryn L. Jones et al.
BIOTECHNIQUES (2007)
Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factor
Silvia Fischer et al.
BLOOD (2007)
Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection
Vincent C. C. Cheng et al.
CLINICAL MICROBIOLOGY REVIEWS (2007)
Priming with SARS CoVS DNA and boosting with SARS CoVS epitopes specific for CD4+ and CD8+ T cells promote cellular immune responses
Jun Huang et al.
VACCINE (2007)
Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice
Mary C. Hu et al.
VACCINE (2007)
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation
Christian Kannemeier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector
Andrew T. Catanzaro et al.
JOURNAL OF INFECTIOUS DISEASES (2006)
A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial
Julie E. Martin et al.
CLINICAL AND VACCINE IMMUNOLOGY (2006)
Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy - a review
Yechiel Becker
VIRUS GENES (2006)
Human memory T cell responses to SARS-CoV E protein
Hui Peng et al.
MICROBES AND INFECTION (2006)
Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, severe acute respiratory syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts
RL Sheets et al.
TOXICOLOGICAL SCIENCES (2006)
Mucosal delivery of vaccine antigens and its advantages in pediatrics
MT De Magistnis
ADVANCED DRUG DELIVERY REVIEWS (2006)
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
FO Nestle et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Effects of multiple copies of CpG on DNA vaccination
AL Zhang et al.
DNA AND CELL BIOLOGY (2005)
Immune responses with DNA vaccines encoded different gene fragments of severe acute respiratory syndrome coronavirus in BALB/c mice
ZJ Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
A novel intranasal Protollin™-based measles vaccine induces mucosal and systemic neutralizing antibody responses and cell-mediated immunity in mice
S Chabot et al.
VACCINE (2005)
Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans
KR Van Kampen et al.
VACCINE (2005)
Isolation of virus from a SARS patient and genome-wide analysis of genetic mutations related to pathogenesis and epidemiology from 47 SARS-CoV isolates
Y Zhu et al.
VIRUS GENES (2005)
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
ZY Yang et al.
NATURE (2004)
Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation
Z Wang et al.
GENE THERAPY (2004)
Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine
P Hai et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Development of stable liquid formulations for adenovirus- based vaccines
RK Evans et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Protollin™:: a novel adjuvant for intranasal vaccines
T Jones et al.
VACCINE (2004)
Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity
UJ Buchholz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Adenoviruses as vaccine vectors
N Tatsis et al.
MOLECULAR THERAPY (2004)
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system
F Lemiale et al.
JOURNAL OF VIROLOGY (2003)
Structural stability of adenovirus type 5
J Rexroad et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Nasal drug delivery - possibilities, problems and solutions
L Illum
JOURNAL OF CONTROLLED RELEASE (2003)
Mucosal immunization with DNA vaccines
P Hobson et al.
METHODS (2003)
Single oral immunization with replication deficient recombinant adenovirus elicits long-lived transgene-specific cellular and humoral immune responses
S Sharpe et al.
VIROLOGY (2002)
Toxicity of a first-generation adenoviral vector in rhesus Macaques
JN Lozier et al.
HUMAN GENE THERAPY (2002)
Development of formulations that enhance physical stability of viral vectors for gene therapy
MA Croyle et al.
GENE THERAPY (2001)
Risk factors for improper vaccine storage and handling in private provider offices
KN Bell et al.
PEDIATRICS (2001)
Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications
GNM Ferreira et al.
TRENDS IN BIOTECHNOLOGY (2000)
Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice
M Dupuis et al.
JOURNAL OF IMMUNOLOGY (2000)
Plasmid DNA vaccines: Investigation of integration into host cellular DNA following intramuscular injection in mice
BJ Ledwith et al.
INTERVIROLOGY (2000)
Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers
TP Le et al.
VACCINE (2000)
The role of CpG motifs in innate immunity
AM Krieg
CURRENT OPINION IN IMMUNOLOGY (2000)