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Role of MRI in idiopathic inflammatory myopathies: a review article

Journal

ACTA RADIOLOGICA
Volume 63, Issue 2, Pages 200-213

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.1177/0284185121990305

Keywords

Idiopathic inflammatory myositis; polymyositis; dermatomyositis; inclusion body myositis; magnetic resonance imaging

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Idiopathic inflammatory myopathies are rare autoimmune conditions characterized by slow, progressive muscle weakness and inflammatory infiltrates. The role of MRI in evaluating disease activity and identifying biopsy sites is well-established, but its use in disease phenotyping is less explored.
Idiopathic inflammatory myopathies are a rare heterogeneous group of chronic, autoimmune conditions characterized by the slow, progressive weakness of the skeletal muscles and inflammatory infiltrates in the muscle tissue. The predominant role of magnetic resonance imaging (MRI) in myositis imaging is to assess disease activity and to identify the target site for biopsy. Its role in phenotyping the disease is less explored. The aim of the present review was to examine the role of MRI in differentiating between the common inflammatory myopathies, i.e. dermatomyositis, polymyositis, and sporadic inclusion body myositis, and to describe the specific spectrum of MRI findings in various inflammatory myopathies.

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