4.7 Article

Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers

Journal

FOOD SCIENCE AND HUMAN WELLNESS
Volume 9, Issue 4, Pages 313-319

Publisher

KEAI PUBLISHING LTD
DOI: 10.1016/j.fshw.2020.04.003

Keywords

Antioxidative activity; Cercis chinensis bunge; Chemical component; alpha-glucosidase

Funding

  1. Key Project in Science and Technology Agency of Henan Province [192102110112, 192102110214, 182102410083]
  2. Innovation Training Program for College Students [201910475107, MSCXSY2019036]

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Antioxidant and alpha-glucosidase inhibitiory active compounds of Cercis chinensis flowers were investigated with bio-assay guiding method. Ethyl acetate fraction (CLEa) and n-butanol fraction (CLBu) exhibited antioxidant and alpha-glucosidase inhibitiory activity in vitro, and the corresponding active fractions, EaFr.3, EaFr.5 and BuFr.1, exhibited higher antioxidant and alpha-glucosidase inhibitiory activity than those of other fractions. Eight compounds, ethyl gallate (1), stearic acid (2), docosanoic acid (3), 5 alpha-stigmast-9(11)-en-3 beta-ol (4), kaempferol-3-O-alpha rhamnopyranoside (5), vanillic acid (6), fisetin (7), and beta-sitosterol (8), were isolated and identified from CLEa and CLBu. Ethyl gallate shown the highest antioxidant activity by scavenging DPPH radical and reducing ferric compared. Docosanoic acid and vanillic acid shown stronger alpha-glucosidase inhibitory activity than that of acarbose. (C) 2020 Beijing Academy of Food Sciences. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

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