Journal
LIFE-BASEL
Volume 11, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/life11010063
Keywords
coronary arteries; inflammation; stent; stent thrombosis; stent restenosis
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Coronary stents are widely implanted medical devices with various mechanical and biochemical characteristics. Inflammatory reactions are a major cause of complications following stent implantation, highlighting the importance of understanding and comparing these reactions across different generations of stents.
Coronary stents belong to the most commonly implanted devices worldwide. A number of different types of stent exist, with very different mechanical and biochemical characteristics that influence their interactions with vascular tissues. Inappropriate inflammatory reactions are the major cause of the two major complications that follow implantation of stents in a percentage as high as 5-20%. It is therefore important to understand these reactions and how different they are among different generations of stents.
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