Journal
LIFE-BASEL
Volume 11, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/life11010034
Keywords
hidradenitis suppurativa; DLQI; quality of life
Categories
Funding
- Biomolecular Analyses for Tailored Medicine in AcneiNversa (BATMAN) project - ERA PerMed
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This study provides robust data on the significant impact of HS on patients' QoL in a cohort of 1795 German patients, showing that women tend to experience higher impairment, especially when the neck is involved. Understanding QoL impairment in such patients is crucial for proper management of this disease.
The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients' quality of life (QoL). The aim of this study was to present more robust data on patients' QoL impairment by demographic data and its correlation with well-known HS risk factors on a cohort of 1795 German patients. The instrument used for measuring QoL in this study was the Dermatology Life Quality Index (DLQI). Overall, patients reported a very large effect of HS on their QoL (mean DLQI: 13.2 +/- 8.1 points), and 22% of the analyzed population even reported to consider the effect as extremely large. Women tended to experience significantly higher impairment than men (p < 0.001). QoL impairment correlated positively with pain (r = 0.581, p < 0.001), HS severity (measured by the International Hidradenitis Suppurativa Severity Score System (IHS4)) as well as Hurley. Neck involvement tended to decrease QoL significantly more than any other location (14.7 +/- 8.3 points). This study confirms the enormous influence of HS on patients' QoL in a large cohort. Knowledge of QoL impairment in such patients is crucial for proper understanding and holistic management of this disease.
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