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Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
Tau protein binds to pericentromeric DNA:: a putative role for nuclear tau in nucleolar organization
Marcela K. Sjoberg et al.
JOURNAL OF CELL SCIENCE (2006)
Increased levels of granular tau oligomers: An early sign of brain aging and Alzheimer's disease
S Maeda et al.
NEUROSCIENCE RESEARCH (2006)
Neuropathologic substrate of mild cognitive impairment
WR Markesbery et al.
ARCHIVES OF NEUROLOGY (2006)
Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis
CG Glabe et al.
NEUROLOGY (2006)
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
VE Kagan et al.
NATURE CHEMICAL BIOLOGY (2005)
In vivo evidence of CHIP up-regulation attenuating tau aggregation
N Sahara et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L Tau transgenic mice
DC David et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners - Implications for neurodegeneration
SF Levy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Microtubule-associated protein tau is a substrate of ATP/Mg2+-dependent proteasome protease system
JY Zhang et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
GB Stokin et al.
SCIENCE (2005)
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
RA Nixon et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mouse centric and pericentric satellite repeats form distinct functional heterochromatin
M Guenatri et al.
JOURNAL OF CELL BIOLOGY (2004)
Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology
AM Cataldo et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
The N-terminal domain of p53 is natively unfolded
R Dawson et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Microtubule-dependent oligomerization of tau - Implications for physiological tau function and tauopathies
V Makrides et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
P Giannakopoulos et al.
NEUROLOGY (2003)
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
R Kayed et al.
SCIENCE (2003)
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
S Keck et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Microtubule associated protein tau binds to double-stranded but not single-stranded DNA
Q Hua et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2003)
Proteasomal degradation of tau protein
DC David et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
K Stamer et al.
JOURNAL OF CELL BIOLOGY (2002)
Epigenetic codes for heterochromatin formation and silencing: Rounding up the usual suspects
EJ Richards et al.
CELL (2002)
FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and tau filaments in forebrain
F Lim et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2001)
Tauopathy in Drosophila:: Neurodegeneration without neurofibrillary tangles
CW Wittmann et al.
SCIENCE (2001)
Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
KM Sakamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Expression of α- and β-globin genes occurs within different nuclear domains in haemopoietic cells
KE Brown et al.
NATURE CELL BIOLOGY (2001)
p53 is associated with cellular microtubules and is transported to the nucleus by dynein
P Giannakakou et al.
NATURE CELL BIOLOGY (2000)
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
L Buée et al.
BRAIN RESEARCH REVIEWS (2000)
Impaired proteasome function in Alzheimer's disease
JN Keller et al.
JOURNAL OF NEUROCHEMISTRY (2000)