Related references
Note: Only part of the references are listed.A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations
Anne T. Reutens et al.
CONTEMPORARY CLINICAL TRIALS (2020)
NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets
Yixuan Zhang et al.
NATURE REVIEWS CARDIOLOGY (2020)
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM-2020 EXECUTIVE SUMMARY
Alan J. Garber et al.
ENDOCRINE PRACTICE (2020)
Molecular complexities underlying the vascular complications of diabetes mellitus - A comprehensive review
Shalini Paul et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2020)
Lipoxin A4 attenuates uric acid-activated, NADPH oxidase-dependent oxidative stress by interfering with translocation of p47phox in human umbilical vein endothelial cells
You Zhou et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)
Canagliflozin for the Treatment of Diabetic Kidney Disease and Implications for Clinical Practice: A Narrative Review
Davida Kruger et al.
DIABETES THERAPY (2020)
Liraglutide Increases Serum Levels of MicroRNA-27b, -130a and -210 in Patients with Type 2 Diabetes Mellitus: A Novel Epigenetic Effect
Rosaria Vincenza Giglio et al.
METABOLITES (2020)
Fibrates Revisited: Potential Role in Cardiovascular Risk Reduction
Nam Hoon Kim et al.
DIABETES & METABOLISM JOURNAL (2020)
Liraglutide protects against diabetes mellitus complicated with focal cerebral ischemic injury by activating mitochondrial ATP-sensitive potassium channels
Ninghua Shi et al.
NEUROREPORT (2019)
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway
Jun Wu et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Myocardial Ischemia and Diabetes Mellitus: Role of Oxidative Stress in the Connection between Cardiac Metabolism and Coronary Blood Flow
Paolo Severino et al.
JOURNAL OF DIABETES RESEARCH (2019)
Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse
Jay C. Jha et al.
DIABETOLOGIA (2019)
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
CongXiao Zhang et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2019)
Anti-Inflammatory and Anti-Hyperuricemic Functions of Two Synthetic Hybrid Drugs with Dual Biological Active Sites
Rafa S. Almeer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension
Shalini M. Krishnan et al.
CARDIOVASCULAR RESEARCH (2019)
Hyperglycemia modulates redox, inflammatory and vasoactive markers through specific signaling pathways in cerebral endothelial cells: Insights on insulin protective action
Angelique Arcambal et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Alpha-lipoic acid and coenzyme Q10 combination ameliorates experimental diabetic neuropathy by modulating oxidative stress and apoptosis
Nasrin Sadeghiyan Galeshkalami et al.
LIFE SCIENCES (2019)
Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes
Joao S. Teodoro et al.
FRONTIERS IN PHYSIOLOGY (2019)
Bardoxolone Methyl Improves Kidney Function in Patients with Chronic Kidney Disease Stage 4 and Type 2 Diabetes: Post-Hoc Analyses from Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Study
Melanie P. Chin et al.
AMERICAN JOURNAL OF NEPHROLOGY (2018)
Neuroprotective Mechanisms of Glucagon-like Peptide-1-based Therapies in Ischaemic Stroke: A Systematic Review based on Pre-Clinical Studies
Ida R. Marlet et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2018)
Role of AGEs in the progression and regression of atherosclerotic plaques
Zhong-qun Wang et al.
GLYCOCONJUGATE JOURNAL (2018)
Protein kinase C drives fibroblast activation and kidney fibrosis by stimulating autophagic flux
Xian Xue et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Supplemental Vitamins and Minerals for CVD Prevention and Treatment
David J. A. Jenkins et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy
Sonia Sifuentes-Franco et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2018)
Early Growth Response 1 (Egr1) Is a Transcriptional Activator of NOX4 in Oxidative Stress of Diabetic Kidney Disease
Fang Hu et al.
JOURNAL OF DIABETES RESEARCH (2018)
Role of ROS and Nutritional Antioxidants in Human Diseases
Zewen Liu et al.
FRONTIERS IN PHYSIOLOGY (2018)
Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With Versus Without Diabetes Mellitus Results From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial)
Robert P. Giugliano et al.
CIRCULATION (2018)
A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes
Jay C. Jha et al.
CLINICAL SCIENCE (2018)
Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis
Eoin P. Brennan et al.
DIABETES (2018)
Neuroprotection of rhGLP-1 in diabetic rats with cerebral ischemia/reperfusion injury via regulation of oxidative stress, EAAT2, and apoptosis
Yi Fang et al.
DRUG DEVELOPMENT RESEARCH (2018)
Recent novel approaches to limit oxidative stress and inflammation in diabetic complications
Raelene J. Pickering et al.
CLINICAL & TRANSLATIONAL IMMUNOLOGY (2018)
Platelet Hyperreactivity in Diabetes: Focus on GPVI Signaling - Are Useful Drugs Already Available?
Jane F. Arthur et al.
DIABETES (2017)
An update on sodium-glucose co-transporter-2 inhibitors for the treatment of diabetes mellitus
Daniel S. Hsia et al.
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2017)
Oxidative stress and diabetic retinopathy: development and treatment
G. D. Calderon et al.
EYE (2017)
SGLT2 Inhibitors as a Therapeutic Option for Diabetic Nephropathy
Daiji Kawanami et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Bruce Neal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Oxidative Stress: Harms and Benefits for Human Health
Gabriele Pizzino et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies
Xinyu Yang et al.
FRONTIERS IN PHYSIOLOGY (2017)
Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis
Xinxin Liu et al.
SCIENTIFIC REPORTS (2017)
Oxidative Stress in Atherosclerosis
Ajoe John Kattoor et al.
CURRENT ATHEROSCLEROSIS REPORTS (2017)
NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy
Jay C. Jha et al.
DIABETES (2017)
Thrombotic and cardiovascular risks in type two diabetes; Role of platelet hyperactivity
Almottesembellah Gaiz et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report
Thomas van der Heijden et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease
Stephen P. Gray et al.
DIABETOLOGIA (2017)
Heart Disease and Stroke Statistics-2017 Update A Report From the American Heart Association
Emelia J. Benjamin et al.
CIRCULATION (2017)
The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction
Arpeeta Sharma et al.
CARDIOVASCULAR DIABETOLOGY (2017)
Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy
Jay C. Jha et al.
DIABETOLOGIA (2016)
PGE2, Kidney Disease, and Cardiovascular Risk: Beyond Hypertension and Diabetes
Rania Nasrallah et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Diabetes and Kidney Disease: Role of Oxidative Stress
Jay C. Jha et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Diabetes mellitus: The linkage between oxidative stress, inflammation, hypercoagulability and vascular complications
Caroline Pereira Domingueti et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2016)
The next generation of therapeutics for chronic kidney disease
Matthew D. Breyer et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Diabetes mellitus statistics on prevalence and mortality: facts and fallacies
Paul Zimmet et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes
Christoph Wanner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
The progress in understanding and treatment of diabetic retinopathy
Alan W. Stitt et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2016)
Efficacy of Febuxostat for Slowing the GFR Decline in Patients With CKD and Asymptomatic Hyperuricemia: A 6-Month, Double-Blind, Randomized, Placebo-Controlled Trial
Dipankar Sircar et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2015)
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement
Sebastian Altenhofer et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications
Ana I. Casas et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases
Paavo Korge et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Bernard Zinman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Lipid Mediators Are Critical in Resolving Inflammation: A Review of the Emerging Roles of Eicosanoids in Diabetes Mellitus
Fernando H. G. Tessaro et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Renin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy. Present Evidences
Luz Lozano-Maneiro et al.
JOURNAL OF CLINICAL MEDICINE (2015)
Effect of Pentoxifylline on Renal Function and Urinary Albumin Excretion in Patients with Diabetic Kidney Disease: The PREDIAN Trial
Juan F. Navarro-Gonzalez et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
MicroRNA-424 Protects Against Focal Cerebral Ischemia and Reperfusion Injury in Mice by Suppressing Oxidative Stress
Ping Liu et al.
STROKE (2015)
Cardiovascular Complications of Diabetic Kidney Disease
Ragnar Palsson et al.
ADVANCES IN CHRONIC KIDNEY DISEASE (2014)
Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials
M. Monami et al.
DIABETES OBESITY & METABOLISM (2014)
Nephropathy and Elevated BP in Mice with Podocyte-Specific NADPH Oxidase 5 Expression
Chet E. Holterman et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Effect of Redox Modulating NRF2 Activators on Chronic Kidney Disease
Bo-hyun Choi et al.
MOLECULES (2014)
Diabetic kidney disease in Australia: Current burden and future projections
Sarah White et al.
NEPHROLOGY (2014)
Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
Johji Nomura et al.
SCIENTIFIC REPORTS (2014)
Diabetes: a 21st century challenge
Paul Z. Zimmet et al.
LANCET DIABETES & ENDOCRINOLOGY (2014)
Nox-4 deletion reduces oxidative stress and injury by PKC-α-associated mechanisms in diabetic nephropathy
Vicki Thallas-Bonke et al.
PHYSIOLOGICAL REPORTS (2014)
NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus-Accelerated Atherosclerosis
Stephen P. Gray et al.
CIRCULATION (2013)
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes
Mona Sedeek et al.
CLINICAL SCIENCE (2013)
The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?
Phillip Shelton et al.
FASEB JOURNAL (2013)
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease
Stacey Ruiz et al.
KIDNEY INTERNATIONAL (2013)
Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
Dick de Zeeuw et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Oxidative stress in vascular disease and its pharmacological prevention
Huige Li et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development
Akifumi Kushiyama et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis
Caroline S. Fox et al.
LANCET (2012)
Sodium-Glucose Cotransporter Inhibition Prevents Oxidative Stress in the Kidney of Diabetic Rats
Horacio Osorio et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Platelets in atherosclerosis
Dirk Lievens et al.
THROMBOSIS AND HAEMOSTASIS (2011)
Protein tyrosine phosphatase PTPεM negatively regulates PDGF β-receptor signaling induced by high glucose and PDGF in vascular smooth muscle cells
Hidehisa Shimizu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse
Phyllis Chew et al.
DIABETES (2010)
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
M. Sedeek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Impact of Fenofibrate on Type 2 Diabetes Patients with Features of the Metabolic Syndrome: Subgroup Analysis From FIELD
Michel P. Hermans
CURRENT CARDIOLOGY REVIEWS (2010)
Site-Specific Antiatherogenic Effect of the Antioxidant Ebselen in the Diabetic Apolipoprotein E-Deficient Mouse
Phyllis Chew et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice
Tomoki Kosugi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
The age/rage axis in diabetes-accelerated atherosclerosis
Karin Jandeleit-Dahm et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)
Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis
LANCET (2008)
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
Anushka Patel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Oxidative stress and vascular disease
NR Madamanchi et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Share Paper
