4.7 Review

Effect of Aging on Homeostasis in the Soft Tissue of the Periodontium: A Narrative Review

Related references

Note: Only part of the references are listed.
Article Dentistry, Oral Surgery & Medicine

Cellular ageing of oral fibroblasts differentially modulates extracellular matrix organization

Srividya Atkuru et al.

Summary: Ageing of oral fibroblasts impairs extracellular matrix production and organization, particularly affecting the structure of ECM fibers which may impact wound healing in the elderly. Aged oral fibroblasts exhibit slower proliferation rate and a senescence phenotype, leading to altered production and organization of ECM proteins such as collagen and fibronectin.

JOURNAL OF PERIODONTAL RESEARCH (2021)

Article Dentistry, Oral Surgery & Medicine

The anti-periodontitis action of metformin via targeting NLRP3 inflammasome

Yongmei Tan et al.

ARCHIVES OF ORAL BIOLOGY (2020)

Article Nutrition & Dietetics

Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women

Jay Jay Thaung Zaw et al.

NUTRIENTS (2020)

Article Biology

Rapamycin rejuvenates oral health in aging mice

Jonathan Y. An et al.

ELIFE (2020)

Review Biotechnology & Applied Microbiology

The quest to slow ageing through drug discovery

Linda Partridge et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Genetics & Heredity

Improved Human Age Prediction by Using Gene Expression Profiles From Multiple Tissues

Fayou Wang et al.

FRONTIERS IN GENETICS (2020)

Article Biochemistry & Molecular Biology

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

Uku Raudvere et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Cell Biology

Fibroblast growth factor-2 inhibits CD40-mediated periodontal inflammation

Chiharu Fujihara et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biochemistry & Molecular Biology

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

Huaiyu Mi et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Biochemistry & Molecular Biology

The Gene Ontology Resource: 20 years and still GOing strong

S. Carbon et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Multidisciplinary Sciences

Senescent cell turnover slows with age providing an explanation for the Gompertz law

Omer Karin et al.

NATURE COMMUNICATIONS (2019)

Review Anatomy & Morphology

Periodontal materials and cell biology for guided tissue and bone regeneration

Mihai Andrei et al.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2018)

Article Dentistry, Oral Surgery & Medicine

SOD2 is upregulated in periodontitis to reduce further inflammation progression

Yong Yoon et al.

ORAL DISEASES (2018)

Article Multidisciplinary Sciences

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

Rafael Radi

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Geriatrics & Gerontology

Oxidative stress, aging, and diseases

Ilaria Liguori et al.

CLINICAL INTERVENTIONS IN AGING (2018)

Review Dentistry, Oral Surgery & Medicine

Histological and immunological characteristics of the junctional epithelium

Masanori Nakamura

JAPANESE DENTAL SCIENCE REVIEW (2018)

Review Biochemistry & Molecular Biology

Matrix Metalloproteinases as Regulators of Periodontal Inflammation

Cavalla Franco et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Dentistry, Oral Surgery & Medicine

Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility

Y. Wu et al.

JOURNAL OF DENTAL RESEARCH (2016)

Article Dentistry, Oral Surgery & Medicine

A Randomized Clinical Trial Evaluating rh-FGF-2/-TCP in Periodontal Defects

D. L. Cochran et al.

JOURNAL OF DENTAL RESEARCH (2016)

Review Dentistry, Oral Surgery & Medicine

The aging mouth: differentiating normal aging from disease

Ira B. Lamster et al.

PERIODONTOLOGY 2000 (2016)

Article Multidisciplinary Sciences

Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva

Suhee Kim et al.

PLOS ONE (2016)

Article Dentistry, Oral Surgery & Medicine

Anti-B lymphocyte immunotherapy is associated with improvement of periodontal status in subjects with rheumatoid arthritis

Juliette Coat et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2015)

Article Dentistry, Oral Surgery & Medicine

Isolation and Characterization of Human Adult Epithelial Stem Cells from the Periodontal Ligament

M. Athanassiou-Papaefthymiou et al.

JOURNAL OF DENTAL RESEARCH (2015)

Review Nursing

Reactive Oxygen and Nitrogen Species Impact on Endothelial Dysfunction

Dereck Salisbury et al.

NURSING RESEARCH (2015)

Review Neurosciences

The Microbiome and Disease: Reviewing the Links between the Oral Microbiome, Aging, and Alzheimer's Disease

Deborah K. Shoemark et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

Article Dentistry, Oral Surgery & Medicine

The molecular and cellular effects of ageing on the periodontal ligament

Won Hee Lim et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2014)

Article Dentistry, Oral Surgery & Medicine

Defective Wound-healing in Aging Gingival Tissue

M. Caceres et al.

JOURNAL OF DENTAL RESEARCH (2014)

Review Peripheral Vascular Disease

Calcium channel blocker-induced gingival enlargement

R. Livada et al.

JOURNAL OF HUMAN HYPERTENSION (2014)

Article Dentistry, Oral Surgery & Medicine

Age-related alterations in gene expression of gingival fibroblasts stimulated with Porphyromonas gingivalis

H. Domon et al.

JOURNAL OF PERIODONTAL RESEARCH (2014)

Article Clinical Neurology

Resveratrol Improves Motoneuron Function and Extends Survival in SOD1G93A ALS Mice

Renzo Mancuso et al.

NEUROTHERAPEUTICS (2014)

Article Dentistry, Oral Surgery & Medicine

Analysis of age-related changes in the functional morphologies of salivary glands in mice

Jeong-Seok Choi et al.

ARCHIVES OF ORAL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Article Biochemistry & Molecular Biology

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Filipe Cabreiro et al.

Article Dentistry, Oral Surgery & Medicine

The distribution and expression of S100A8 and S100A9 in gingival epithelium of mice

K. Nishii et al.

JOURNAL OF PERIODONTAL RESEARCH (2013)

Article Dentistry, Oral Surgery & Medicine

Effects of bFGF on the Modulation of Apoptosis in Gingival Fibroblasts with Different Host Ages

Kotaro Tanimoto et al.

INTERNATIONAL JOURNAL OF DENTISTRY (2013)

Review Dentistry, Oral Surgery & Medicine

Tooth-PDL-bone complex: Response to compressive loads encountered during mastication - A review

Gili R. S. Naveh et al.

ARCHIVES OF ORAL BIOLOGY (2012)

Article Dentistry, Oral Surgery & Medicine

Role of the junctional epithelium in periodontal innate defense and homeostasis

Y. Tsukamoto et al.

JOURNAL OF PERIODONTAL RESEARCH (2012)

Article Genetics & Heredity

A New Definition of Aging?

Thomas Flatt

Frontiers in Genetics (2012)

Article Dentistry, Oral Surgery & Medicine

Oestrogen inhibits osteoclast formation induced by periodontal ligament fibroblasts

Nutthamon Wattanaroonwong et al.

ARCHIVES OF ORAL BIOLOGY (2011)

Article Dentistry, Oral Surgery & Medicine

FGF-2 Stimulates Periodontal Regeneration: Results of a Multi-center Randomized Clinical Trial

M. Kitamura et al.

JOURNAL OF DENTAL RESEARCH (2011)

Article Dentistry, Oral Surgery & Medicine

Apoptotic Genes are Differentially Expressed in Aged Gingival Tissue

O. A. Gonzalez et al.

JOURNAL OF DENTAL RESEARCH (2011)

Article Multidisciplinary Sciences

Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice

Ellen Gerhardt et al.

PLOS ONE (2011)

Review Multidisciplinary Sciences

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

Douglas R. Green et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

Oxidative damage to RNA: mechanisms, consequences, and diseases

Qiongman Kong et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2010)

Article Dentistry, Oral Surgery & Medicine

Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis

Ulvi Kahraman Gursoy et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2010)

Article Dentistry, Oral Surgery & Medicine

Effects of cementum-dentine junction and cementum on the mechanical response of tooth supporting structure

L. M. Ren et al.

JOURNAL OF DENTISTRY (2010)

Article Dentistry, Oral Surgery & Medicine

Comprehensive analysis of gene expression in the junctional epithelium by laser microdissection and microarray analysis

Y. Hayashi et al.

JOURNAL OF PERIODONTAL RESEARCH (2010)

Article Biochemistry & Molecular Biology

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

David Warde-Farley et al.

NUCLEIC ACIDS RESEARCH (2010)

Review Dentistry, Oral Surgery & Medicine

Bacterial invasion of epithelial cells and spreading in periodontal tissue

Gena D. Tribble et al.

PERIODONTOLOGY 2000 (2010)

Article Cell Biology

DNA damage response and cellular senescence in tissues of aging mice

Chunfang Wang et al.

AGING CELL (2009)

Article Biochemistry & Molecular Biology

Inflammatory and bone-related genes are modulated by aging in human periodontal ligament cells

Bruno Braga Benatti et al.

CYTOKINE (2009)

Article Biochemistry & Molecular Biology

Mechanical Force Induces Type I Collagen Expression in Human Periodontal Ligament Fibroblasts Through Activation of ERK/JNK and AP-1

Sung-Ho Kook et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Article Dentistry, Oral Surgery & Medicine

Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade

Marcela Hernandez Rios et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2009)

Article Dentistry, Oral Surgery & Medicine

Identification of Pathogen and Host-Response Markers Correlated With Periodontal Disease

Christoph A. Ramseier et al.

JOURNAL OF PERIODONTOLOGY (2009)

Article Multidisciplinary Sciences

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

David E. Harrison et al.

NATURE (2009)

Review Dentistry, Oral Surgery & Medicine

RANK/RANKL/OPG during orthodontic tooth movement

M. Yamaguchi

ORTHODONTICS & CRANIOFACIAL RESEARCH (2009)

Review Dermatology

Hyaluronan in skin: aspects of aging and its pharmacologic modulation

Robert Stern et al.

CLINICS IN DERMATOLOGY (2008)

Article Cell Biology

Influence of Aging on Biological Properties of Periodontal Ligament Cells

Bruno Braga Benatti et al.

CONNECTIVE TISSUE RESEARCH (2008)

Article Biochemistry & Molecular Biology

g:Profiler -: a web-based toolset for functional profiling of gene lists from large-scale experiments

Jueri Reimand et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Cell Biology

Extracellular matrix-mediated tissue remodeling following axial movement of teeth

Xianghong Luan et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)

Article Multidisciplinary Sciences

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur et al.

NATURE (2006)

Article Oncology

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

Mahvash Zakikhani et al.

CANCER RESEARCH (2006)

Article Dentistry, Oral Surgery & Medicine

Matrix metalloproteinase-13 is highly expressed in destructive periodontal disease activity

Marcela Hernandez et al.

JOURNAL OF PERIODONTOLOGY (2006)

Article Dentistry, Oral Surgery & Medicine

Gingival tissue and crevicular fluid co-operation in adult periodontitis

A Beklen et al.

JOURNAL OF DENTAL RESEARCH (2006)

Article Multidisciplinary Sciences

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

GC Kujoth et al.

SCIENCE (2005)

Article Dentistry, Oral Surgery & Medicine

Age-related changes in human sublingual glands: a post mortem study

LR Azevedo et al.

ARCHIVES OF ORAL BIOLOGY (2005)

Article Medicine, General & Internal

Global burden of hypertension: analysis of worldwide data

PM Kearney et al.

LANCET (2005)

Article Multidisciplinary Sciences

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

JG Wood et al.

NATURE (2004)

Article Medicine, General & Internal

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

JCW Edwards et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Dentistry, Oral Surgery & Medicine

Clinical course of chronic periodontitis -: I.: Role of gingivitis

M Schätzle et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2003)

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

Article Cell Biology

Nitric oxide signaling specificity - the heart of the problem

DS Bredt

JOURNAL OF CELL SCIENCE (2003)

Article Dentistry, Oral Surgery & Medicine

The induction of c-fos mRNA expression by mechanical stress in human periodontal ligament cells

N Yamaguchi et al.

ARCHIVES OF ORAL BIOLOGY (2002)

Article Neurosciences

Induction of α-synuclein aggregation by intracellular nitrative insult

E Paxinou et al.

JOURNAL OF NEUROSCIENCE (2001)

Review Dentistry, Oral Surgery & Medicine

Molecular and cell biology of the gingiva

PM Bartold et al.

PERIODONTOLOGY 2000 (2000)