Journal
JOURNAL OF FUNGI
Volume 7, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/jof7010030
Keywords
Aspergillus fumigatus; conidium; germination; asynchrony; transcriptome; aspergillosis
Categories
Funding
- French national reference center for Primary Immunodeficiencies (CEREDIH, Hopital Necker-Enfants Malades, Paris, France)
- la Fondation pour la Recherche Medicale [DEQ20150331722 LATGE Equipe FRM 2015]
- CEREDIH
Ask authors/readers for more resources
The germination of Aspergillus fumigatus is shown to be asynchronous, regardless of the nutritional environment and extensive gene deletions. The reasons for this asynchrony remain unknown, but it is essential for the completion of the biological cycle of this filamentous fungus.
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other species of filamentous fungi. We show here that the germination of A. fumigatus is asynchronous. If the nutritional environment and extensive gene deletions can modify the germination parameters for A. fumigatus, the asynchrony is maintained in all germinative conditions tested. Even though the causes for this asynchrony of conidial germination remain unknown, asynchrony is essential for the completion of the biological cycle of this filamentous fungus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available