Journal
NPJ REGENERATIVE MEDICINE
Volume 6, Issue 1, Pages -Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41536-020-00111-1
Keywords
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Categories
Funding
- National Institutes of Health [R35GM128831, R21OD028211, R21OD028209, R2112095457]
- National Science Foundation [1636007]
- W.M. Keck Foundation
- Schweizerischer Nationalfonds zur Forderung der Wissenschaftlichen Forschung Early Postdoc Mobility Fellowship [P2BEP3_181707]
- Swiss National Science Foundation (SNF) [P2BEP3_181707] Funding Source: Swiss National Science Foundation (SNF)
- Directorate For Engineering
- Div Of Civil, Mechanical, & Manufact Inn [1636007] Funding Source: National Science Foundation
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The spiny mouse is an exciting research organism due to its remarkable scarless healing abilities in various tissues beyond the skin, which could shed light on numerous clinically relevant human diseases. However, there are challenges in working with this emerging research organism that require future strategies and methods.
The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.
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