Journal
ACS OMEGA
Volume 5, Issue 49, Pages 31963-31973Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsomega.0c04865
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Funding
- National Natural Science Foundation of China [21672200, 21772185]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
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An electrochemical synthesis for quinazolines and quinazolinones was developed via a C(sp(3))-H amination/C-N cleavage by virtue of the anodic oxidation. The reaction can be carried out in aqueous media under mild conditions to afford the desired products with high yields. The reaction mechanism was proposed after detailed investigation.
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