4.2 Review

An evidence map of actigraphy studies exploring longitudinal associations between rest-activity rhythms and course and outcome of bipolar disorders

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Summary: This study reveals the relationship between rest-activity rhythms and lithium response, suggesting that rest-activity rhythms can serve as predictors of lithium treatment response in bipolar disorder patients. The study suggests that more stable circadian rhythms and lower sleep variability may be associated with a good response to lithium.

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