Journal
ANTIOXIDANTS
Volume 9, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/antiox9121227
Keywords
ascorbic acid; blood pressure; coronavirus; COVID– 19; dietary supplements; drug formulations; endothelial dysfunction; GULO; heart failure; hypertension; infections; liposomes; oxidative stress; stroke; SVCT; vascular permeability; Vitamin C
Funding
- NIH [R01-DK123259, R01-HL146691, R01-DK033823, R00-DK107895, R56-AG066431]
- American Heart Association [AHA-20POST35211151]
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The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart disease, heart failure, hypertension, and cerebrovascular diseases. Pitfalls and controversies in investigations on vitamin C and cardiovascular disorders are also discussed.
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