Related references
Note: Only part of the references are listed.Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective
Lucie Peterkova et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics
Ilari Tarvainen et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Mitotic Poisons in Research and Medicine
Jan Skubnik et al.
MOLECULES (2020)
Structural modification of trilobolide for upgrading its immunobiological properties and reducing its cytotoxic action
Juraj Harmatha et al.
FITOTERAPIA (2019)
A Phase II, Multicenter, Single-Arm Study of Mipsagargin (G-202) as a Second-Line Therapy Following Sorafenib for Adult Patients with Progressive Advanced Hepatocellular Carcinoma
Devalingam Mahalingam et al.
CANCERS (2019)
Thapsigargin induces apoptosis in adrenocortical carcinoma by activating endoplasmic reticulum stress and the JNK signaling pathway: an in vitro and in vivo study
Lili Wu et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2019)
Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate cancer
Emmanuel S. Akinboye et al.
ASIAN JOURNAL OF UROLOGY (2019)
Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis
Tomas Zimmermann et al.
MOLECULES (2018)
2-fluoro-5-maleimidobenzoic acid-linked albumin drug (MAD) delivery for selective systemic targeting of metastatic prostate cancer
Emmanuel S. Akinboye et al.
PROSTATE (2018)
Thapsigargin induces apoptosis of prostate cancer through cofilin-1 and paxillin
Fengyu Huang et al.
ONCOLOGY LETTERS (2018)
Production Technologies of Pharmacologically Active Sesquiterpene Lactones
A. S. Kishkentayeva et al.
EURASIAN CHEMICO-TECHNOLOGICAL JOURNAL (2018)
Scalable Synthesis of (-)-Thapsigargin
Hang Chu et al.
ACS CENTRAL SCIENCE (2017)
Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response
Pankaj Sehgal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Immunoassay for determination of trilobolide
Lukas Huml et al.
STEROIDS (2017)
Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours
D. Mahalingam et al.
BRITISH JOURNAL OF CANCER (2016)
Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation
Zhiqiang Ma et al.
SCIENTIFIC REPORTS (2016)
Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide
Nhu Thi Quynh Doan et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Thapsigargin-From Thapsia L. to Mipsagargin
Trine Bundgaard Andersen et al.
MOLECULES (2015)
Supramolecular hydrogels constructed by red-light-responsive host-guest interactions for photo-controlled protein release in deep tissue
Dongsheng Wang et al.
SOFT MATTER (2015)
Targeting thapsigargin towards tumors
Nhu Thi Quynh Doan et al.
STEROIDS (2015)
Concise synthesis of thapsigargin from nortrilobolide
Francois Crestey et al.
TETRAHEDRON LETTERS (2015)
Tailor-Made Fluorescent Trilobolide To Study Its Biological Relevance
Michal Jurasek et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology
M. M. R. de Melo et al.
JOURNAL OF SUPERCRITICAL FLUIDS (2014)
Sesquiterpene lactones: Adverse health effects and toxicity mechanisms
M. Helena R. Amorim et al.
CRITICAL REVIEWS IN TOXICOLOGY (2013)
Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
Samuel R. Denmeade et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Semisynthesis of Ingenol 3-Angelate (PEP005): Efficient Stereoconservative Angeloylation of Alcohols
Xifu Liang et al.
SYNLETT (2012)
Mitosis-targeted anti-cancer therapies: where they stand
K-S Chan et al.
CELL DEATH & DISEASE (2012)
Sesquiterpene lactone trilobolide activates production of interferon-γ and nitric oxide
Eva Kmonickova et al.
FITOTERAPIA (2010)
Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs
Anne-Marie L. Winther et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Total synthesis of five thapsigargins:: Guaianolide natural products exhibiting sub-nanomolar SERCA inhibition
Stephen P. Andrews et al.
CHEMISTRY-A EUROPEAN JOURNAL (2007)
Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells
H Sohoel et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug
S Janssen et al.
PROSTATE (2006)
Synthesis of the thapsigargins
SV Ley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer
SR Denmeade et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)
Design, synthesis, and pharmacological evaluation of thapsigargin analogues for targeting apoptosis to prostatic cancer cells
CM Jakobsen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)