Related references
Note: Only part of the references are listed.Prognostic value of periostin in multiple solid cancers: A systematic review with meta-analysis
Tao Yang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer
Daniela Unterleuthner et al.
ANGIOGENESIS (2020)
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts
Yongle Zhang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome
Elisa D'Arcangelo et al.
BRITISH JOURNAL OF CANCER (2020)
Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts
Takahiro Yamanaka et al.
BRITISH JOURNAL OF CANCER (2020)
VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling
Zhuan Zhou et al.
CANCER LETTERS (2020)
HALO 109-301: A randomized, double-blind, placebo-controlled, phase 3 study of pegvorhyaluronidase alfa (PEGPH20) + nab-paclitaxel/gemcitabine (AG) in patients (pts) with previously untreated hyaluronan (HA)-high metastatic pancreatic ductal adenocarcinoma (mPDA).
Margaret A. Tempero et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
Floriane Pelon et al.
NATURE COMMUNICATIONS (2020)
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
Handong Ma et al.
CELL REPORTS (2020)
miR-210 transferred by lung cancer cell-derived exosomes may act as proangiogenic factor in cancer-associated fibroblasts by modulating JAK2/STAT3 pathway
Junqiang Fan et al.
CLINICAL SCIENCE (2020)
A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming
Michael Cangkrama et al.
EMBO MOLECULAR MEDICINE (2020)
Novel module and hub genes of distinctive breast cancer associated fibroblasts identified by weighted gene co-expression network analysis
Yangguang Xu et al.
BREAST CANCER (2020)
Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated (vol 10, 50, 2020)
Jessica Bauer et al.
SCIENTIFIC REPORTS (2020)
The multifarious roles of the chemokine CXCL14 in cancer progression and immune responses
Joseph A. Westrich et al.
MOLECULAR CARCINOGENESIS (2020)
Human fibronectin extra domain B as a biomarker for targeted therapy in cancer
Relinde I. Y. Lieverse et al.
MOLECULAR ONCOLOGY (2020)
Role of Tumor and Stroma-Derived IGF/IGFBPs in Pancreatic Cancer
Divya Thomas et al.
CANCERS (2020)
STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy
Esther N. Arwert et al.
NATURE CELL BIOLOGY (2020)
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
Zeda Zhang et al.
CANCER CELL (2020)
Epigenetics in modulating immune functions of stromal and immune cells in the tumor microenvironment
Xingyi Pan et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2020)
Fibroblast Reprogramming in Gastrointestinal Cancer
Maria-Theodora Melissari et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer
Lisa M. Becker et al.
CELL REPORTS (2020)
Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy
Jiaqi Li et al.
MOLECULES (2020)
A framework for advancing our understanding of cancer-associated fibroblasts
Erik Sahai et al.
NATURE REVIEWS CANCER (2020)
The tumor microenvironment and radiotherapy response; a central role for cancer-associated fibroblasts
Marleen Ansems et al.
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2020)
Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI
Jian-Wei Wang et al.
ONCOLOGY RESEARCH (2019)
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
Cassandra Ringuette Goulet et al.
BMC CANCER (2019)
VEGF in Signaling and Disease: Beyond Discovery and Development
Rajendra S. Apte et al.
CELL (2019)
Interaction between IGF2-PI3K axis and cancer-associated-fibroblasts promotes anal squamous carcinogenesis
Wulfran Cacheux et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
Neel I. Nissen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Toll-Like Receptor 4 and Matrix Metalloproteases 11 and 13 as Predictors of Tumor Recurrence and Survival in Stage II Colorectal Cancer
Noemi Eiro et al.
PATHOLOGY & ONCOLOGY RESEARCH (2019)
Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer
Rongsheng Zhang et al.
CELL DEATH & DISEASE (2019)
Antibody-Cytokine Fusions: Versatile Products for the Modulation of Anticancer Immunity
Dario Neri
CANCER IMMUNOLOGY RESEARCH (2019)
Cancer-Associated Fibroblasts' Functional Heterogeneity in Pancreatic Ductal Adenocarcinoma
Mohammad Awaji et al.
CANCERS (2019)
Differential MicroRNA Landscape Triggered by Estrogens in Cancer Associated Fibroblasts (CAFs) of Primary and Metastatic Breast Tumors
Adele Vivacqua et al.
CANCERS (2019)
Tumor Extracellular Matrix Remodeling: New Perspectives as a Circulating Tool in the Diagnosis and Prognosis of Solid Tumors
Marta Giussani et al.
CELLS (2019)
Cancer-associated fibroblasts in radiotherapy: challenges and new opportunities
Zhanhuai Wang et al.
CELL COMMUNICATION AND SIGNALING (2019)
Transforming Growth Factor-β Signaling in Immunity and Cancer
Eduard Batlle et al.
IMMUNITY (2019)
Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer The SUNSHINE Randomized Clinical Trial
Kimmie Ng et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)
Extracellular vesicles in the tumor microenvironment: old stories, but new tales
Liu Han et al.
MOLECULAR CANCER (2019)
CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer
J. L. Hu et al.
MOLECULAR CANCER (2019)
Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts
Yutaka Naito et al.
ONCOGENE (2019)
Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation
Rodrigo Berzaghi et al.
CANCERS (2019)
Role of Exosomes in Crosstalk Between Cancer-Associated Fibroblasts and Cancer Cells
Xi Yang et al.
FRONTIERS IN ONCOLOGY (2019)
Exosomal miRNA-106b from cancer-associated fibroblast promotes gemcitabine resistance in pancreatic cancer
Yuan Fang et al.
EXPERIMENTAL CELL RESEARCH (2019)
Cancer-associated fibroblast-derived exosomal miR-382-5p promotes the migration and invasion of oral squamous cell carcinoma
Li-Ping Sun et al.
ONCOLOGY REPORTS (2019)
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Ela Elyada et al.
CANCER DISCOVERY (2019)
Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer
Zigian Li et al.
CELLS (2019)
Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment
Tianyi Liu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts
Yosuke Mitsui et al.
ONCOLOGY RESEARCH (2019)
Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth
Shoshi Hisamitsu et al.
HUMAN CELL (2019)
Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
Pino Bordignon et al.
CELL REPORTS (2019)
A Snapshot of The Tumor Microenvironment in Colorectal Cancer: The Liquid Biopsy
Mercedes Herrera et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
miRNAs derived from cancer-associated fibroblasts in colorectal cancer
Amir Savardashtaki et al.
EPIGENOMICS (2019)
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts
Tushar D. Bhagat et al.
ELIFE (2019)
Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer
Huiran Yue et al.
BMC CANCER (2019)
Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma
Cindy Neuzillet et al.
JOURNAL OF PATHOLOGY (2019)
Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment
Michinobu Umakoshi et al.
ONCOGENE (2019)
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Eva A. Ebbing et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome
Alin Rai et al.
PROTEOMICS (2019)
Differentially expressed genes ASPN, COL1A1, FN1, VCAN and MUC5AC are potential prognostic biomarkers for gastric cancer
Kaiyuan Jiang et al.
ONCOLOGY LETTERS (2019)
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
Giulia Biffi et al.
CANCER DISCOVERY (2019)
Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer
Nicholas Willumsen et al.
SCIENTIFIC REPORTS (2019)
Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma
Mauricio Rocha Dourado et al.
JOURNAL OF EXTRACELLULAR VESICLES (2019)
Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5
Xing Qin et al.
GENOME BIOLOGY (2019)
Prognostic value of the immunohistochemical detection of cancer-associated fibroblasts in oral cancer: A systematic review and meta-analysis
Mauricio Rocha Dourado et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2018)
A core matrisome gene signature predicts cancer outcome
Arseniy E. Yuzhalin et al.
BRITISH JOURNAL OF CANCER (2018)
Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway
Guangyao Dai et al.
BULLETIN DU CANCER (2018)
Ovarian cancer-derived extracellular vesicles affect normal human fibroblast behavior
Ilaria Giusti et al.
CANCER BIOLOGY & THERAPY (2018)
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
Ana Costa et al.
CANCER CELL (2018)
Nab-paclitaxel interrupts cancer-stromal interaction through C-X-C motif chemokine 10-mediated interleukin-6 downregulation in vitro
Rui Feng et al.
CANCER SCIENCE (2018)
CD10+ GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
Shicheng Su et al.
CELL (2018)
The IGF2/IR/IGF1R Pathway in Tumor Cells and Myofibroblasts Mediates Resistance to EGFR Inhibition in Cholangiocarcinoma
Javier Vaquero et al.
CLINICAL CANCER RESEARCH (2018)
Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Haaglim Cho et al.
CLINICAL CANCER RESEARCH (2018)
Enduring epigenetic landmarks define the cancer microenvironment
Ruth Pidsley et al.
GENOME RESEARCH (2018)
The prognostic value of tumor-stroma ratio in tumor-positive axillary lymph nodes of breast cancer patients
Kiki M. H. Vangangelt et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
The Role of the Estrogen Pathway in the Tumor Microenvironment
Natalie J. Rothenberger et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma
Simona Principe et al.
JOURNAL OF PROTEOME RESEARCH (2018)
Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2-and CXCL8-mediated cancer cell migration
Bianca Cioni et al.
MOLECULAR ONCOLOGY (2018)
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Daniele V. F. Tauriello et al.
NATURE (2018)
Phenotype molding of stromal cells in the lung tumor microenvironment
Diether Lambrechts et al.
NATURE MEDICINE (2018)
Shedding light on the cell biology of extracellular vesicles
Guillaume van Niel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β
Yan Lan et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury
Feihong Deng et al.
CELL DEATH & DISEASE (2018)
Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer
Tian Fang et al.
NATURE COMMUNICATIONS (2018)
Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer
Noomi Vainer et al.
Oncotarget (2018)
Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype
Bastian Doersam et al.
FRONTIERS IN IMMUNOLOGY (2018)
Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade
Rikke B. Holmgaard et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer
Francesca Andriani et al.
BMC CANCER (2018)
Tumour-stroma ratio and prognosis in gastric adenocarcinoma
Niko Kemi et al.
BRITISH JOURNAL OF CANCER (2018)
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
Sanjeev Mariathasan et al.
NATURE (2018)
Comparing the expression profiles of steroid hormone receptors and stromal cell markers in prostate cancer at different Gleason scores
Thomas Gevaert et al.
SCIENTIFIC REPORTS (2018)
Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGF beta Inhibitor Sequencing in Melanoma
Fei Zhao et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer
Davide Melisi et al.
BRITISH JOURNAL OF CANCER (2018)
Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation
Andrea Clocchiatti et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Melanoma cell-secreted exosomal miR-1555p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway
Xiaocheng Zhou et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer
Lusheng Wei et al.
CELL DEATH & DISEASE (2018)
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7
Binbin Yu et al.
CELL DEATH & DISEASE (2018)
TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
Ankur Chakravarthy et al.
NATURE COMMUNICATIONS (2018)
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
Michael Bartoschek et al.
NATURE COMMUNICATIONS (2018)
Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation
Joke Tommelein et al.
CANCER RESEARCH (2018)
Cancer-Associated Fibroblasts Accelerate Malignant Progression of Non-Small Cell Lung Cancer via Connexin 43-Formed Unidirectional Gap Junctional Intercellular Communication
Min Luo et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
The ratio of cancer cells to stroma after induction therapy in the treatment of non-small cell lung cancer
Masaki Goto et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)
Stromal factors involved in human prostate cancer development, progression and castration resistance
Noemi Eiro et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)
Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells
Y. Deng et al.
ONCOGENE (2017)
Matrix stiffening promotes a tumor vasculature phenotype
Francois Bordeleau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
Marco Demaria et al.
CANCER DISCOVERY (2017)
Androgen receptor in cancer-associated fibroblasts influences stemness in cancer cells
Chun-peng Liao et al.
ENDOCRINE-RELATED CANCER (2017)
Regulation of the mammalian heat shock factor 1
Sharadha Dayalan Naidu et al.
FEBS JOURNAL (2017)
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Daniel Ohlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
The IGF-I/IGF-IR Signaling System and Pancreatic Cancer
E. P. Kopantzev et al.
MOLECULAR GENETICS MICROBIOLOGY AND VIROLOGY (2017)
Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells
Thomas Kryza et al.
MOLECULAR ONCOLOGY (2017)
Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms
C. Unger et al.
ONCOGENE (2017)
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
Pasquale Sansone et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells
Wenqian Li et al.
ONCOTARGET (2017)
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Xiongyan Wu et al.
ONCOTARGET (2017)
Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion
Linda Ziani et al.
ONCOTARGET (2017)
Cancer-associated fibroblasts support vascular growth through mechanical force
Mary Kathryn Sewell-Loftin et al.
SCIENTIFIC REPORTS (2017)
Metabolism shapes the tumor microenvironment
Miguel Reina-Campos et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Microenvironmental regulation of tumour angiogenesis
Michele de Palma et al.
NATURE REVIEWS CANCER (2017)
Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expression
Dong Tang et al.
TUMOR BIOLOGY (2016)
Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer
Elin Sjoberg et al.
BRITISH JOURNAL OF CANCER (2016)
Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA
Le Qu et al.
CANCER CELL (2016)
Vascular mimicry formation is promoted by paracrine TGF-β and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma
Jine Yang et al.
CANCER LETTERS (2016)
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling
Xuguang Yang et al.
CANCER RESEARCH (2016)
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors
Lucy Ireland et al.
CANCER RESEARCH (2016)
Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation
Qian Xiao et al.
CANCER RESEARCH (2016)
Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
Lifeng Yang et al.
CELL METABOLISM (2016)
Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma
Elisabete F. Carapuca et al.
JOURNAL OF PATHOLOGY (2016)
Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis
Zhe Wang et al.
JOURNAL OF PATHOLOGY (2016)
Letrozole-induced functional changes in carcinoma-associated fibroblasts and their influence on breast cancer cell biology
Kaifu Li et al.
MEDICAL ONCOLOGY (2016)
Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations
Daniella Bianchi-Frias et al.
MOLECULAR CANCER RESEARCH (2016)
Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK
Paul A. Toste et al.
MOLECULAR CANCER RESEARCH (2016)
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Cristovao M. Sousa et al.
NATURE (2016)
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Sebastian R. Nielsen et al.
NATURE CELL BIOLOGY (2016)
Epigenetic control of the tumor microenvironment
David L. Marks et al.
EPIGENOMICS (2016)
Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1
Chi Lam Au Yeung et al.
NATURE COMMUNICATIONS (2016)
Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway
Leilei Tao et al.
SCIENTIFIC REPORTS (2016)
Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling
Tristan Rupp et al.
CELL REPORTS (2016)
TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis
Xing Qin et al.
SCIENTIFIC REPORTS (2016)
THBS2 is a Potential Prognostic Biomarker in Colorectal Cancer
Xue Wang et al.
SCIENTIFIC REPORTS (2016)
ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells
Muge Sarper et al.
SCIENTIFIC REPORTS (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
Eishu Hirata et al.
CANCER CELL (2015)
Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer
Lisa Ryner et al.
CLINICAL CANCER RESEARCH (2015)
Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
I. Acerbi et al.
INTEGRATIVE BIOLOGY (2015)
BRAF Inhibition Generates a Host-Tumor Niche that Mediates Therapeutic Escape
Inna V. Fedorenko et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
Alexandre Calon et al.
NATURE GENETICS (2015)
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
Jean Albrengues et al.
NATURE COMMUNICATIONS (2015)
TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT
Junlong Zhuang et al.
SCIENTIFIC REPORTS (2015)
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts
Fernando Calvo et al.
CELL REPORTS (2015)
CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
Eunyoung Chun et al.
CELL REPORTS (2015)
A phenotype from tumor stroma based on the expression of metalloproteases and their inhibitors, associated with prognosis in breast cancer
Noem Eiro et al.
ONCOIMMUNOLOGY (2015)
Direct Interaction between Carcinoma Cells and Cancer Associated Fibroblasts for the Regulation of Cancer Invasion
Hideki Yamaguchi et al.
CANCERS (2015)
Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation
Laia Gorchs et al.
FRONTIERS IN ONCOLOGY (2015)
Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes
J. P. Webber et al.
ONCOGENE (2015)
Simultaneous Irradiation of Fibroblasts and Carcinoma Cells Repress the Secretion of Soluble Factors Able to Stimulate Carcinoma Cell Migration
Adnan Arshad et al.
PLOS ONE (2015)
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
Holly E. Barker et al.
NATURE REVIEWS CANCER (2015)
Stromal Androgen Receptor in Prostate Development and Cancer
Mandeep Singh et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
Berna C. Oezdemir et al.
CANCER CELL (2014)
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Andrew D. Rhim et al.
CANCER CELL (2014)
The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
Ruth Scherz-Shouval et al.
CELL (2014)
Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
Mara H. Sherman et al.
CELL (2014)
POSTN/TGFBI-associated stromal signature predicts poor prognosis in serous epithelial ovarian cancer
Beth Y. Karlan et al.
GYNECOLOGIC ONCOLOGY (2014)
Antitumor Efficacy of the Anti-Interleukin-6 (IL-6) Antibody Siltuximab in Mouse Xenograft Models of Lung Cancer
Lanxi Song et al.
JOURNAL OF THORACIC ONCOLOGY (2014)
Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial
Martin Reck et al.
LANCET ONCOLOGY (2014)
Differences between CAFs and their paired NCF from adjacent colonic mucosa reveal functional heterogeneity of CAFs, providing prognostic information
Mireia Berdiel-Acer et al.
MOLECULAR ONCOLOGY (2014)
The Prognostic Significance of Cancer-Associated Fibroblasts in Esophageal Squamous Cell Carcinoma
Sang Yun Ha et al.
PLOS ONE (2014)
Prognostic relevance of cancer-associated fibroblasts in human cancer
Janna Paulsson et al.
SEMINARS IN CANCER BIOLOGY (2014)
Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling
Wan-Jiun Chen et al.
NATURE COMMUNICATIONS (2014)
Prognostic Significance in Breast Cancer of a Gene Signature Capturing Stromal PDGF Signaling
Oliver Frings et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically
Tracy L. Putoczki et al.
CANCER CELL (2013)
RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Jianya Huan et al.
CANCER RESEARCH (2013)
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
Ning Ding et al.
CELL (2013)
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
Joseph M. Curry et al.
CELL CYCLE (2013)
Tumor Grade and Matrix Metalloproteinase 2 Expression in Stromal Fibroblasts Help to Stratify the High-Risk Group of Patients With Early Breast Cancer Identified on the Basis of St Gallen Recommendations
Joanna Niemiec et al.
CLINICAL BREAST CANCER (2013)
Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma
Abasi Ene-Obong et al.
GASTROENTEROLOGY (2013)
Interleukin-13 and transforming growth factor β synergise in the pathogenesis of human intestinal fistulae
Michael Scharl et al.
GUT (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion
Shengqiang Yu et al.
MEDICAL ONCOLOGY (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Changes in the Secretory Profile of NSCLC-Associated Fibroblasts after Ablative Radiotherapy: Potential Impact on Angiogenesis and Tumor Growth
Turid Hellevik et al.
TRANSLATIONAL ONCOLOGY (2013)
The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin
Osvaldo Pontiggia et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
Alexandre Calon et al.
CANCER CELL (2012)
CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells
Akihiro Tsuyada et al.
CANCER RESEARCH (2012)
Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
Tania Fiaschi et al.
CANCER RESEARCH (2012)
Immunocytokines: a novel class of potent armed antibodies
Nadine Pasche et al.
DRUG DISCOVERY TODAY (2012)
Comprehensive care and care at the center of the new recommendation HAS
Elisa Derrien
ACTUALITES PHARMACEUTIQUES (2012)
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Ravid Straussman et al.
NATURE (2012)
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
Timothy R. Wilson et al.
NATURE (2012)
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
Yu Sun et al.
NATURE MEDICINE (2012)
Targeting the TGFβ signalling pathway in disease
Rosemary J. Akhurst et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Serum interleukin-6 as a prognostic biomarker in patients with metastatic melanoma
Lise Hoejberg et al.
MELANOMA RESEARCH (2012)
Multicenter, randomized study of genetically modified recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in cancer patients receiving chemotherapy
Shikai Wu et al.
SUPPORTIVE CARE IN CANCER (2012)
Interactions between cancer stem cells and their niche govern metastatic colonization
Ilaria Malanchi et al.
NATURE (2012)
Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis
Omar E. Franco et al.
CANCER RESEARCH (2011)
Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer
Jermaine Coward et al.
CLINICAL CANCER RESEARCH (2011)
Retinoic Acid-Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt-β-Catenin Signaling to Slow Tumor Progression
Fieke E. M. Froeling et al.
GASTROENTEROLOGY (2011)
Role of periostin in cancer progression and metastasis: Inhibition of breast cancer progression and metastasis by anti-periostin antibody in a murine model
Mariko Kyutoku et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2011)
The Role of Tumor Stroma in Cancer Progression and Prognosis Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer
Roy M. Bremnes et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation
Andrew C. Newman et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
Wei Tan et al.
NATURE (2011)
Effects of Androgen Receptor and Androgen on Gene Expression in Prostate Stromal Fibroblasts and Paracrine Signaling to Prostate Cancer Cells
Matthew J. Tanner et al.
PLOS ONE (2011)
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
Neta Erez et al.
CANCER CELL (2010)
Clinical and Correlative Results of SWOG S0354: A Phase II Trial of CNTO328 (Siltuximab), a Monoclonal Antibody against Interleukin-6, in Chemotherapy-Pretreated Patients with Castration-Resistant Prostate Cancer
Tanya B. Dorff et al.
CLINICAL CANCER RESEARCH (2010)
Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial-mesenchymal transition-like state in breast cancer cells in vitro
Ming-Qing Gao et al.
JOURNAL OF CELL SCIENCE (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Yasushi Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Signaling by members of the TGF-beta family in vascular morphogenesis and disease
Evangelia Pardali et al.
TRENDS IN CELL BIOLOGY (2010)
PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment
Yongping Crawford et al.
CANCER CELL (2009)
Expression and prognostic significance of metalloproteases and their inhibitors in luminal A and basal-like phenotypes of breast carcinoma
Luis O. Gonzalez et al.
HUMAN PATHOLOGY (2009)
CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer
Yoichi Matsuo et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
VEGF and inhibitors of TGFβ type-I receptor kinase synergistically promote blood-vessel formation by inducing α5-integrin expression
Zhen Liu et al.
JOURNAL OF CELL SCIENCE (2009)
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Mirna Balsamo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
Li Yang et al.
CANCER CELL (2008)
BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
Frank Hilberg et al.
CANCER RESEARCH (2008)
Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations
Seiji Yano et al.
CANCER RESEARCH (2008)
The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis
Kazuhiro Noma et al.
GASTROENTEROLOGY (2008)
Decrease in stromal androgen receptor associates with androgen-independent disease and promotes prostate cancer cell proliferation and invasion
Yirong Li et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
Wen Qiu et al.
NATURE GENETICS (2008)
Stromal gene expression predicts clinical outcome in breast cancer
Greg Finak et al.
NATURE MEDICINE (2008)
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting
Kristian Pietras et al.
PLOS MEDICINE (2008)
ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells
A. Safina et al.
ONCOGENE (2007)
Loss of transforming growth factor-β type II receptor promotes metastatic head-and-neck squamous cell carcinoma
Shi-Long Lu et al.
GENES & DEVELOPMENT (2006)
Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
AK Rodningen et al.
RADIOTHERAPY AND ONCOLOGY (2005)
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
O Casanovas et al.
CANCER CELL (2005)
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
A Orimo et al.
CELL (2005)
Phase I/II dose escalation study of recombinant human interleukin-11 following ifosfamicle, carboplatin and etoposide in children, adolescents and young adults with solid tumours or lymphoma: a clinical, haematological and biological study
MS Cairo et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
R Salgado et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Synergistic cooperation between hypoxia and transforming growth factor-β pathways on human vascular endothelial growth factor gene expression
T Sánchez-Elsner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
