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Sebastian I. Arriola Apelo et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2016)
Mitophagy plays a central role in mitochondrial ageing
Alan Diot et al.
MAMMALIAN GENOME (2016)
The Mitochondrial Basis of Aging
Nuo Sun et al.
MOLECULAR CELL (2016)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg et al.
NATURE MEDICINE (2016)
Nuclear DNA damage signalling to mitochondria in ageing
Evandro Fei Fang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Erin Quan Toyama et al.
SCIENCE (2016)
Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties
Valentina Izzo et al.
TRENDS IN CELL BIOLOGY (2016)
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity
Siming Ma et al.
ELIFE (2016)
Cyclophilin D Is Involved in the Regulation of Autophagy and Affects the Lifespan of P. anserina in Response to Mitochondrial Oxidative Stress
Piet Kramer et al.
FRONTIERS IN GENETICS (2016)
Erastin Disrupts Mitochondrial Permeability Transition Pore (mPTP) and Induces Apoptotic Death of Colorectal Cancer Cells
Haizhong Huo et al.
PLOS ONE (2016)
It takes two to tango: NAD+ and sirtuins in aging/longevity control
Shin-ichiro Imai et al.
NPJ AGING AND MECHANISMS OF DISEASE (2016)
DNA repair and aging: the impact of the p53 family
Sara Nicolai et al.
AGING-US (2015)
Dietary restriction, mitochondrial function and aging: from yeast to humans
Andrea Ruetenik et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Mitochondrial dysfunction in aging: Much progress but many unresolved questions
Brendan A. I. Payne et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
The role of mitochondrial dysfunction in age-related diseases
Rebecca K. Lane et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Mitochondrial ROS Signaling in Organismal Homeostasis
Gerald S. Shadel et al.
CELL (2015)
Promoting Health and Longevity through Diet: From Model Organisms to Humans
Luigi Fontana et al.
CELL (2015)
Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
Moshi Song et al.
CELL METABOLISM (2015)
How Mitochondrial Dynamism Orchestrates Mitophagy
Orian S. Shirihai et al.
CIRCULATION RESEARCH (2015)
PINK1/Parkin-mediated mitophagy in mammalian cells
Akinori Eiyama et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
ROS-dependent signal transduction
Colleen R. Reczek et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Poly-ADP-ribosylation signaling during DNA damage repair
Barbara Golia et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2015)
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications
Thomas M. Durcan et al.
GENES & DEVELOPMENT (2015)
Essential role for autophagy in life span extension
Frank Madeo et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D
T. Bochaton et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling
Heide Christine Patterson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
Alban Ordureau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan
Claire E. Schaar et al.
PLOS GENETICS (2015)
Mitochondrial Dysfunction and alpha-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?
Michela Zaltieri et al.
PARKINSONS DISEASE (2015)
Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri
Chiara Priami et al.
AGING AND DISEASE (2015)
Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation
Sibel Kahraman et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2015)
Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessed ex Vivo under Conditions Mimicking Rest and Exercise
Renata L. S. Goncalves et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models
Alessandra Zulian et al.
HUMAN MOLECULAR GENETICS (2014)
The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice
Lee J. Martin et al.
NEUROBIOLOGY OF AGING (2014)
MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AND ROS-INDUCED ROS RELEASE
Dmitry B. Zorov et al.
PHYSIOLOGICAL REVIEWS (2014)
Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death
C-J Lin et al.
CELL DEATH & DISEASE (2014)
Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells
X. Zhou et al.
CELL DEATH & DISEASE (2014)
The sirtuins, oxidative stress and aging: an emerging link
Philip I. Merksamer et al.
AGING-US (2013)
Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health
Tiago R. Figueira et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Crosstalk between apoptosis, necrosis and autophagy
Vassiliki Nikoletopoulou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Signaling the mitochondrial unfolded protein response
Mark W. Pellegrino et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
3-Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway
Maria E. Solesio et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
Ana P. Gomes et al.
CELL (2013)
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Laurent Mouchiroud et al.
CELL (2013)
Oxidative damage to macromolecules in human Parkinson disease and the rotenone model
Laurie H. Sanders et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Exploiting the Role of Resveratrol in Rat Mitochondrial Permeability Transition
Yue Zhang et al.
JOURNAL OF MEMBRANE BIOLOGY (2013)
Changes in the mitochondrial permeability transition pore in aging and age-associated diseases
Giuseppe Paradies et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2013)
The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration
Costanza Savino et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Permeability Transition Pore-Mediated Mitochondrial Superoxide Flashes Regulate Cortical Neural Progenitor Differentiation
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PLOS ONE (2013)
ROS-Mediated PARP Activity Undermines Mitochondrial Function After Permeability Transition Pore Opening During Myocardial Ischemia-Reperfusion
Jacqueline M. Schriewer et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
Induction of the permeability transition pore in cells depleted of mitochondrial DNA
Ionica Masgras et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
Angelina V. Vaseva et al.
CELL (2012)
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
Tomohiko Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats
Antonio Ascensao et al.
CLINICAL SCIENCE (2011)
Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts
David Cotan et al.
FASEB JOURNAL (2011)
Influence of aging on membrane permeability transition in brain mitochondria
Julia Toman et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca2+stress in astrocyte
Mei-Jie Jou
JOURNAL OF PINEAL RESEARCH (2011)
Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia
Jose Lumini-Oliveira et al.
MITOCHONDRION (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
Regulation of autophagy by ROS: physiology and pathology
Ruth Scherz-Shouval et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
Angela V. Hafner et al.
AGING-US (2010)
Cyclophilin D in mitochondrial pathophysiology
Valentina Giorgio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)
Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
Eugenia Morselli et al.
AGING-US (2009)
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening
Giuseppe Petrosillo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy
Angeles Rodriguez-Hernandez et al.
AUTOPHAGY (2009)
Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis
Flora Tomasello et al.
CELL RESEARCH (2009)
Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection
Merce Pallas et al.
CURRENT NEUROVASCULAR RESEARCH (2009)
Mechanism for resveratrol-induced cardioprotection against reperfusion injury involves glycogen synthase kinase 3β and mitochondrial permeability transition pore
Jinkun Xi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening
Gurpreet S. Bhamra et al.
BASIC RESEARCH IN CARDIOLOGY (2008)
Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria
Irina G. Sava et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Differential involvement of mitochondrial permeability transition in cytotoxicity of 1-methyl-4-phenylpyridinium and 6-hydroxydopamine
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MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)
The mitochondrial permeability transition from in vitro artifact to disease target
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FEBS JOURNAL (2006)
Exercise training induces respiratory substrate-specific decrease in Ca2+-induced permeability transition pore opening in heart mitochondria
M Marcil et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition
F Di Lisa et al.
CARDIOVASCULAR RESEARCH (2005)
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection
D Hausenloy et al.
CIRCULATION (2004)
Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for antiapoptotic effects of melatonin
SA Andrabi et al.
FASEB JOURNAL (2004)
Mitochondria and aging: a role for the permeability transition?
M Crompton
AGING CELL (2004)
Metformin inhibits mitochondrial permeability transition and cell death:: a pharmacological in vitro study
B Guigas et al.
BIOCHEMICAL JOURNAL (2004)
Autophagy genes are essential for dauer development and life-span extension in C-elegans
A Meléndez et al.
SCIENCE (2003)
The regulation of AMP-activated protein kinase by H2O2.
SL Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
The mitochondrial permeability transition, release of cytochrome c and cell death -: Correlation with the duration of pore openings in situ
V Petronilli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart
F Di Lisa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
R Betarbet et al.
NATURE NEUROSCIENCE (2000)