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LA Ehrlich et al.
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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
MJ Kiel et al.
CELL (2005)
A2A adenosine receptor induction inhibits IFN-γ production in murine CD4+ T cells
CM Lappas et al.
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Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells
F Jundt et al.
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Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
EM Hurt et al.
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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
DJ Ceradini et al.
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Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines
C Houde et al.
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Cellular niches controlling B lymphocyte behavior within bone marrow during development
K Tokoyoda et al.
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The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity
YC Nie et al.
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Anti-α4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis
Y Mori et al.
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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
E Tian et al.
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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
P Staller et al.
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Transforming growth factor-β1 down-regulates expression of chemokine stromal cell-derived factor-1:: functional consequences in cell migration and adhesion
N Wright et al.
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PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow:: evidence for cooperation between E-selectin ligands and α4 integrin
Y Katayama et al.
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A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
MV Dhodapkar et al.
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Expression and function of chemokine receptors in human multiple myeloma
C Moller et al.
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Human myeloma cells stimulate the receptor activator of nuclear factor-κB ligand (RANKL) in T lymphocytes:: a potential role in multiple myeloma bone disease
N Giuliani et al.
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Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
V Groh et al.
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The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity
HAM Wols et al.
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Exosomes:: Composition, biogenesis and function
C Théry et al.
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Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response
AE Hauser et al.
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S Stier et al.
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Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications
D Gupta et al.
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A coordinated change in chemokine responsiveness guides plasma cell movements
DC Hargreaves et al.
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Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1
F Sanz-Rodríguez et al.
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The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
FN Karanu et al.
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