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Nras in melanoma: Targeting the undruggable target
Mario Mandala et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2014)
Aldehyde dehydrogenases in cancer: an opporunity for biomaker and drug development?
Klaus Pors et al.
DRUG DISCOVERY TODAY (2014)
Twist1 expression induced by sunitinib accelerates tumor cell vasculogenic mimicry by increasing the population of CD133+ cells in triple-negative breast cancer
Danfang Zhang et al.
MOLECULAR CANCER (2014)
The Antiproliferative Activity of Kinase Inhibitors in Chronic Myeloid Leukemia Cells Is Mediated by FOXO Transcription Factors
Francesca Pellicano et al.
STEM CELLS (2014)
Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence
Yingxi Xu et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population
Rachel Eyre et al.
TUMOR BIOLOGY (2014)
Vascular channels formed by subpopulations of PECAM1+ melanoma cells
James M. Dunleavey et al.
NATURE COMMUNICATIONS (2014)
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
Limo Chen et al.
NATURE COMMUNICATIONS (2014)
The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics
Maximilian Boesch et al.
ONCOTARGET (2014)
ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer
Katharina Feldinger et al.
ONCOTARGET (2014)
ABCG2-Meditated Multidrug Resistance and Tumor-Initiating Capacity of Side Population Cells from Colon Cancer
Zheng-Yuan Xie et al.
ONCOLOGY RESEARCH AND TREATMENT (2014)
ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors
Cheng-Po Huang et al.
CANCER LETTERS (2013)
HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab
Suthinee Ithimakin et al.
CANCER RESEARCH (2013)
The involvement of Notch signaling in melanoma vasculogenic mimicry
Amalia Vartanian et al.
CLINICAL AND EXPERIMENTAL MEDICINE (2013)
Relevant markers of cancer stem cells indicate a poor prognosis in hepatocellular carcinoma patients: a meta-analysis
Yu-Cheng Ma et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2013)
Radiation-Induced Notch Signaling in Breast Cancer Stem Cells
Chann Lagadec et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Tumour heterogeneity and cancer cell plasticity
Corbin E. Meacham et al.
NATURE (2013)
The causes and consequences of genetic heterogeneity in cancer evolution
Rebecca A. Burrell et al.
NATURE (2013)
CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancer
T. J. Liu et al.
ONCOGENE (2013)
The Role of MET Receptor Tyrosine Kinase in Non-Small Cell Lung Cancer and Clinical Development of Targeted Anti-MET Agents
Kyle W. Robinson et al.
ONCOLOGIST (2013)
ALDH1-High Ovarian Cancer Stem-Like Cells Can Be Isolated from Serous and Clear Cell Adenocarcinoma Cells, and ALDH1 High Expression Is Associated with Poor Prognosis
Takafumi Kuroda et al.
PLOS ONE (2013)
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
Min Yu et al.
SCIENCE (2013)
A new perspective of vasculogenic mimicry: EMT and cancer stem cells
Yun-Long Fan et al.
ONCOLOGY LETTERS (2013)
Lung cancer tumorigenicity and drug resistance are enhanced through ALDHhiCD44hi tumor initiating cells
Jing Liu et al.
ONCOTARGET (2013)
Cancer Stem Cells: Distinct Entities or Dynamically Regulated Phenotypes?
Yunqing Li et al.
CANCER RESEARCH (2012)
Zinc finger E-box binding homeobox 1 promotes vasculogenic mimicry in colorectal cancer through induction of epithelial-to-mesenchymal transition
Zhiyong Liu et al.
CANCER SCIENCE (2012)
The developing cancer stem-cell model: clinical challenges and opportunities
Louis Vermeulen et al.
LANCET ONCOLOGY (2012)
Blockade of JAK2-mediated extrinsic survival signals restores sensitivity of CML cells to ABL inhibitors
E. Traer et al.
LEUKEMIA (2012)
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Marco Gerlinger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Ionizing Radiation Induces Stemness in Cancer Cells
Laura Ghisolfi et al.
PLOS ONE (2012)
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
Christina Scheel et al.
SEMINARS IN CANCER BIOLOGY (2012)
VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth
Natasha Y. Frank et al.
CANCER RESEARCH (2011)
ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease
Maria Soledad Sosa et al.
CLINICAL CANCER RESEARCH (2011)
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
Christian Hurtz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast Cancer
Gabriel L. Fiszman et al.
INTERNATIONAL JOURNAL OF BREAST CANCER (2011)
In Situ Identification of Putative Cancer Stem Cells by Multiplexing ALDH1, CD44, and Cytokeratin Identifies Breast Cancer Patients with Poor Prognosis
Veronique Neumeister et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry
Soufiane El Hallani et al.
BRAIN (2010)
Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
James P. Sullivan et al.
CANCER RESEARCH (2010)
Regulation of the Embryonic Morphogen Nodal by Notch4 Facilitates Manifestation of the Aggressive Melanoma Phenotype
Katharine M. Hardy et al.
CANCER RESEARCH (2010)
High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer
Christel van den Hoogen et al.
CANCER RESEARCH (2010)
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
Sreenath V. Sharma et al.
CELL (2010)
Expression and Functional Significance of Twist1 in Hepatocellular Carcinoma: Its Role in Vasculogenic Mimicry
Tao Sun et al.
HEPATOLOGY (2010)
The embryonic morphogen, Nodal, is associated with channel-like structures in human malignant melanoma xenografts
Josephine C. McAllister et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2010)
ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome
Ting Li et al.
LABORATORY INVESTIGATION (2010)
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
Lucia Ricci-Vitiani et al.
NATURE (2010)
Glioblastoma stem-like cells give rise to tumour endothelium
Rong Wang et al.
NATURE (2010)
Breast cancer chemoresistance: Emerging importance of cancer stem cells
Suebwong Chuthapisith et al.
SURGICAL ONCOLOGY-OXFORD (2010)
mTOR Inhibitor RAD001 (Everolimus) Has Antiangiogenic/Vascular Properties Distinct from a VEGFR Tyrosine Kinase Inhibitor
Heidi A. Lane et al.
CLINICAL CANCER RESEARCH (2009)
Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab
Alessandra Magnifico et al.
CLINICAL CANCER RESEARCH (2009)
Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers
Tomonori Tanei et al.
CLINICAL CANCER RESEARCH (2009)
p38α and p38γ Mediate Oncogenic ras-induced Senescence through Differential Mechanisms
Jinny Kwong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on hedgehog pathway activation
Christine Dierks et al.
CANCER CELL (2008)
Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations
Seiji Yano et al.
CANCER RESEARCH (2008)
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
Xiaoxian Li et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
H. Korkaya et al.
ONCOGENE (2008)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
Maria M. Ho et al.
CANCER RESEARCH (2007)
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling
Susumu Kobayashi et al.
CANCER RESEARCH (2006)
The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors
Jeffrey A. Engelman et al.
CLINICAL CANCER RESEARCH (2006)
Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
Phillip C. C. Liu et al.
CANCER BIOLOGY & THERAPY (2006)
Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia
DWJ van der Schaft et al.
CANCER RESEARCH (2005)
A distinct side population of cells with high drug efflux capacity in human tumor cells
C Hirschmann-Jax et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)