IBS-Symptoms in IBD Patients-Manifestation of Concomitant or Different Entities

Irritable bowel syndrome (IBS) is a functional heterogenous disease with a multifactorial pathogenesis. It is characterized by abdominal pain, discomfort, and alteration in gut motility. The occurrence of similar symptoms was observed in patients in clinical remission of inflammatory bowel diseases (IBD) that is Crohn's disease (CD) and ulcerative colitis (UC), which pathogenesis is also not fully understood. Hence, arose the question if these symptoms are true IBS imposed on IBD, or is it a subclinical form of IBD or even pre-IBD? In this article, based on a narrative overview of the literature, we try to find an answer to this query by discussing the pathogenesis and overlaps between these conditions.

Automated summary

Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) have overlapping symptoms and relationships, with still unclear pathogenesis. Similar symptoms of IBS have been observed in some patients during remission of IBD, raising questions about the connection between these two conditions.