Journal
CHEMISTRYSELECT
Volume 6, Issue 4, Pages 663-679Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.202004029
Keywords
Cyclization; electrochemistry; organoselenium; regioselectivity; stereoselectivity
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The growing interest in organoselenium compounds has had a significant impact in medicinal and material chemistry, with recent advancements focusing on catalytic roles and synthetic approaches. This review aims to provide an overview of these developments and contribute towards the future improvement of organoselenium compounds.
The ever-growing interest for organoselenium compounds amongst the chemists has made commendable impact in the field of medicinal chemistry, material chemistry, chemical biology and biochemistry. Researchers have progressively contributed in the development of organoselenium compounds over the years which has been periodically reviewed. On the similar note, this review attempts at providing an overview of the recent advances made in organoselenium chemistry while covering their catalytic indulgence in different transformational approaches, their role in asymmetric synthesis, and synthetic approaches steering their synthesis. These approaches encompass selenofunctionalization and/or cyclization, electrochemical selenylation, bromolactonization, [2,3]- or [1,2]-sigmatropic rearrangement reactions among others. Herein, we have focused on the synthetic approaches developed for the past three years that have not been covered in previously reviewed scientific material. With the knowledge of the recent progress covered, this review could contribute towards future development of organoselenium compounds along with the improvement of the current status.
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