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Aldo-Keto Reductases in the Eye
Shun Ping Huang et al.
JOURNAL OF OPHTHALMOLOGY (2010)
Kinetic studies of AKR1B10, human aldose reductase-like protein: Endogenous substrates and inhibition by steroids
Satoshi Endo et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
The 1.85 Å Structure of an 8R-Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity
David B. Neau et al.
BIOCHEMISTRY (2009)
Resolvins and protectins: mediating solutions to inflammation
Payal Kohli et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative
Bengt Persson et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Prostaglandin F2 Synthase Activities of AldoKeto Reductase 1B1, 1B3 and 1B7
Zakayi Kabututu et al.
JOURNAL OF BIOCHEMISTRY (2009)
Aldo-keto Reductase Family 1 Member B10 Promotes Cell Survival by Regulating Lipid Synthesis and Eliminating Carbonyls
Chun Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers
Chong Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Phosphatidylethanolamine-esterified Eicosanoids in the Mouse TISSUE LOCALIZATION AND INFLAMMATION-DEPENDENT FORMATION IN Th-2 DISEASE
Alwena H. Morgan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cyclooxygenase in normal human tissues - is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?
Nina Zidar et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Update of the LIPID MAPS comprehensive classification system for lipids
Eoin Fahy et al.
JOURNAL OF LIPID RESEARCH (2009)
Cyclooxygenases: structural and functional insights
Carol A. Rouzer et al.
JOURNAL OF LIPID RESEARCH (2009)
Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)
Luigi Di Costanzo et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Philippe Lefebvre et al.
PHYSIOLOGICAL REVIEWS (2009)
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production
David R. Bauman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma
Hans-Erik Claesson
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2009)
Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450
Maude Fer et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases
James P. Hardwick
BIOCHEMICAL PHARMACOLOGY (2008)
Catalytic mechanism and substrate specificity of the β-subunit of the voltage-gated potassium channel
Srinivas M. Tipparaju et al.
BIOCHEMISTRY (2008)
THE ALDO-KETO REDUCTASE SUPERFAMILY AND ITS ROLE IN DRUG METABOLISM AND DETOXIFICATION
Oleg A. Barski et al.
DRUG METABOLISM REVIEWS (2008)
Sex hormone effects on body fluid regulation
Nina S. Stachenfeld
EXERCISE AND SPORT SCIENCES REVIEWS (2008)
Oxygenation of arachidonoyl lysophospholipids by lipoxygenases from soybean, porcine leukocyte, or rabbit reticulocyte
Long Shuang Huang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Functional coupling between the Kv1.1 channel and aldoketoreductase Kvβ1
Yaping Pan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans:: CYP4F3B is the prominent player in PUFA metabolism
Maude Fer et al.
JOURNAL OF LIPID RESEARCH (2008)
Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure
Ansari M. Aleem et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells
Stina Feltenmark et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data
Jongkeun Choi et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Studies on the cholesterol-free mouse -: Strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol
Maura Heverin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase
Benjamin H. Maskrey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes
Matthew Spite et al.
BIOCHEMICAL JOURNAL (2007)
Anandamide metabolism by human liver and kidney microsomal cytochrome P450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides
Natasha T. Snider et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
LMSD: LIPID MAPS structure database
Manish Sud et al.
NUCLEIC ACIDS RESEARCH (2007)
Sterol 14 alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms
Galina I. Lepesheva et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2007)
Complex reactions catalyzed by cytochrome P450 enzymes
Ernre M. Isin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2007)
Glycosylation regulates turnover of cyclooxygenase-2
Mary B. Sevigny et al.
FEBS LETTERS (2006)
Human and mouse eLOX3 have distinct substrate specificities: Implications for their linkage with lipoxygenases in skin
Zheyong Yu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies
Eric Di Luccio et al.
BIOCHEMICAL JOURNAL (2006)
Resolvin E2: Identification and anti-inflammatory actions: Pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis
Eric Tjonahen et al.
CHEMISTRY & BIOLOGY (2006)
Partnering between monomers of cyclooxygenase-2 homodimers
C Yuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cholesterol-metabolizing cytochromes P450
IA Pikuleva
DRUG METABOLISM AND DISPOSITION (2006)
AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer
TL Rizner et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2006)
Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
T Grosser et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta
X Tang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2
SF Kim et al.
SCIENCE (2005)
The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins:: Novel oxygenase products from ω-3 polyunsaturated fatty acids
M Arita et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Potentiation of uterine effects of prostaglandin F2α by adenosine 5′-triphosphate
AU Ziganshin et al.
OBSTETRICS AND GYNECOLOGY (2005)
Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis
M Arita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells:: Alternative subcellular enzyme compartmentation may contribute to carcinogenesis
YK Leung et al.
CANCER RESEARCH (2005)
Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily
E Barbosa-Sicard et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production. (vol 174, pg 2619, 2005)
EP Ryan et al.
JOURNAL OF IMMUNOLOGY (2005)
Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E-2
AV Sampey et al.
ARTHRITIS RESEARCH & THERAPY (2005)
Crystal structure of human prostaglandin F synthase (AKR1C3)
J Komoto et al.
BIOCHEMISTRY (2004)
Regulatory mechanism and physiological role of cytosolic phospholipase A2
T Hirabayashi et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)
The rat leukocyte-type 12-lipoxygenase exhibits an intrinsic hepoxilin A3 synthase activity
S Nigam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
AH Payne et al.
ENDOCRINE REVIEWS (2004)
Characterization of htAKR, a novel gene product in the aldo-keto reductase family specifically expressed in human testis
Y Azuma et al.
MOLECULAR HUMAN REPRODUCTION (2004)
A single active site residue directs oxygenation stereospecificity in lipoxygenases: Stereocontrol is linked to the position of oxygenation
G Coffa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Identification of hepoxilin A3 in inflammatory events:: A required role in neutrophil migration across intestinal epithelia
RJ Mrsny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
DR Nelson et al.
PHARMACOGENETICS (2004)
Cycloxygenase-2 is expressed in vasculature of normal and ischemic adult human kidney and is colocalized with vascular prostaglandin E2 EP4 receptors
KL Therland et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain
N Mast et al.
BIOCHEMISTRY (2003)
A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385
SW Rowlinson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity
M Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Closing the gap:: I dentification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis
Z Marijanovic et al.
MOLECULAR ENDOCRINOLOGY (2003)
Fluorescence resonance energy transfer analysis of cytochromes P4502C2 and 2E1 molecular interactions in living cells
E Szczesna-Skorupa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase
ZY Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+
M Strokin et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases
CA Rouzer et al.
CHEMICAL REVIEWS (2003)
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells -: Autacoids in anti-inflammation
S Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Suicidal inactivation of the rabbit 15-lipoxygenase by 15S-HpETE is paralleled by covalent modification of active site peptides
R Wiesner et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Density-functional investigation on the mechanism of H-atom abstraction by lipoxygenase
N Lehnert et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2003)
The aldo-keto reductase superfamily homepage
D Hyndman et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2003)
A theoretical study of radical-only and combined radical/carbocationic mechanisms of arachidonic acid cyclooxygenation by prostaglandin H synthase
PJ Silva et al.
THEORETICAL CHEMISTRY ACCOUNTS (2003)
Novel homodimeric and heterodimeric rat γ-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins
VP Kelly et al.
BIOCHEMICAL JOURNAL (2002)
Metabolism of 4β-hydroxycholesterol in Humans
K Bodin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Selective oxygenation of N-arachidonylglycine by cyclooxygenase-2
JJ Prusakiewicz et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
The enzymology of prostaglandin endoperoxide H synthases-1 and-2
WL Smith et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2002)
Prostaglandin and leukotriene ω-hydroxylases
Y Kikuta et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2002)
The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding
M Walther et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2 - A critical role for serine 530 and valine 349
C Schneider et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Antiepileptic drugs increase plasma levels of 4β-hydroxycholesterol in humans -: Evidence for involvement of cytochrome P450 3A4
K Bodin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
From brain to bile -: Evidence that conjugation and ω-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans
I Björkhem et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis
M Walther et al.
CHEMISTRY & BIOLOGY (2001)
A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1:: Cloning, physical mapping, and expression
P Krieg et al.
GENOMICS (2001)
Cytochromes P450 and metabolism of xenobiotics
P Anzenbacher et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression
R Spanbroek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Covalently linked heme in cytochrome P4504A fatty acid hydroxylases
U Hoch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Enzymic characterization of epidermis-derived 12-lipoxygenase isoenzymes
M Siebert et al.
BIOCHEMICAL JOURNAL (2001)
Clinical measurement of steroid metabolism
R Andrew
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Detection and cellular localization of 12R-lipoxygenase in human tonsils
C Schneider et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)
Binding of pyridine coenzymes to the β-subunit of the voltage sensitive potassium channels
SQ Liu et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2001)
The reactive oxygen species- and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the α,β-unsaturated aldehyde 4-hydroacy-2-nonenal to 1,4-dihydroxy-2-nonene
ME Burczynski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The N-terminal β-barrel domain of 5-lipoxygenase is essential for nuclear membrane translocation
XS Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural basis for lipoxygenase specificity - Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis
K Schwarz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity
T Hammarberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The bile acid synthetic gene 3β-hydroxy-Δ5-C27-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis
M Schwarz et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2
KR Kozak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
CN Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily:: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
TM Penning et al.
BIOCHEMICAL JOURNAL (2000)
Cyclooxygenase mechanisms
LJ Marnett
CURRENT OPINION IN CHEMICAL BIOLOGY (2000)
Human fatty acid ω-hydroxylase, CYP4A11:: determination of complete genomic sequence and characterization of purified recombinant protein
H Kawashima et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Molecular basis for the transport of cytochrome P450 2E1 to the plasma membrane
EPA Neve et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products
ED Thuresson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Stereoselective biosynthesis of hepoxilin B3 in human epidermis
R Antón et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)
Oxysterols: Modulators of cholesterol metabolism and other processes
GJ Schroepfer
PHYSIOLOGICAL REVIEWS (2000)
Mammalian microsomal cytochrome P450 monooxygenase: Structural adaptations for membrane binding and functional diversity
PA Williams et al.
MOLECULAR CELL (2000)