Related references
Note: Only part of the references are listed.Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation[S]
Anne-Marie Lundsgaard et al.
JOURNAL OF LIPID RESEARCH (2020)
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
Gordon Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
Stephanie J. Alexopoulos et al.
NATURE COMMUNICATIONS (2020)
Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance
Lia R. Edmunds et al.
MOLECULAR METABOLISM (2020)
Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis
Michelle L. Boland et al.
NATURE METABOLISM (2020)
Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis
Steven Young et al.
HEPATOLOGY COMMUNICATIONS (2020)
Urolithin A, a Gut Metabolite, Improves Insulin Sensitivity Through Augmentation of Mitochondrial Function and Biogenesis
Ashley Mulcahy Toney et al.
OBESITY (2019)
Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy
Tao Zhou et al.
REDOX BIOLOGY (2019)
Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Maria Isabel Hernandez-Alvarez et al.
CELL (2019)
Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice
Nina L. Gluchowski et al.
HEPATOLOGY (2019)
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondria! Fragmentation in Obesity
Philipp Hammerschmidt et al.
CELL (2019)
Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma
Kenichiro Enooku et al.
SCIENTIFIC REPORTS (2019)
Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates
Leigh Goedeke et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Progressive Liver Disease in Patients With Ataxia Telangiectasia
Helena Donath et al.
FRONTIERS IN PEDIATRICS (2019)
Nanoparticle-mediated lysosomal reacidification restores mitochondrial turnover and function in cells under lipotoxicity
Essam A. Assali et al.
FASEB JOURNAL (2019)
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy
Xinyang Yu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2019)
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD
Daniel Garcia et al.
CELL REPORTS (2019)
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide
Chirag Vasavda et al.
CELL CHEMICAL BIOLOGY (2019)
Endogenous non-enzymatic antioxidants in the human body
Iwona Mironczuk-Chodakowska et al.
ADVANCES IN MEDICAL SCIENCES (2018)
Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases
Abdoh Taleb et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
Tatsuya Yamada et al.
CELL METABOLISM (2018)
Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion
Ilan Y. Benador et al.
CELL METABOLISM (2018)
Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis
Maria Apostolopoulou et al.
DIABETES CARE (2018)
Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
Jiska van der Reest et al.
NATURE COMMUNICATIONS (2018)
Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling
Carly S. Cox et al.
CELL METABOLISM (2018)
AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo
Marc Foretz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
Elizabeth C. Hinchy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression
Kang-Yu Peng et al.
JOURNAL OF LIPID RESEARCH (2018)
Beneficial and Paradoxical Roles of Anti-Oxidative Nutritional Support for Non-Alcoholic Fatty Liver Disease
Daisuke Uchida et al.
NUTRIENTS (2018)
Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis
Kyle S. McCommis et al.
HEPATOLOGY (2017)
The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease A meta-analysis (PRISMA) of randomized control trials
Sheng Zhong et al.
MEDICINE (2017)
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species
Rebecca C. Rabinovitch et al.
CELL REPORTS (2017)
The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity
Adam J. Rauckhorst et al.
MOLECULAR METABOLISM (2017)
A Randomized Trial of Silymarin for the Treatment of Nonalcoholic Steatohepatitis
Chan Wah Kheong et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2017)
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation (vol 26, pg 394, 2017)
Chai-Wan Kim et al.
CELL METABOLISM (2017)
Meta-Analysis of Randomized Controlled Trials of Pharmacologic Agents in Non-alcoholic Steatohepatitis
Adnan Said et al.
ANNALS OF HEPATOLOGY (2017)
Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives
Federico Salomone et al.
LIVER INTERNATIONAL (2016)
In Cellulo Mapping of Subcellular Localized Bilirubin
Jong-Seok Park et al.
ACS CHEMICAL BIOLOGY (2016)
Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin
Sameer S. Kulkarni et al.
DIABETES (2016)
Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice
Troy L. Merry et al.
DIABETOLOGIA (2016)
Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy
Rui Ni et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
c-Jun N-Terminal Kinase Mediates Mouse Liver Injury Through a Novel Sab (SH3BP5)-Dependent Pathway Leading to Inactivation of Intramitochondrial Src
Sanda Win et al.
HEPATOLOGY (2016)
Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity
Kyle M. Trudeau et al.
JOURNAL OF CELL BIOLOGY (2016)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Erin Quan Toyama et al.
SCIENCE (2016)
Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53
Young Mi Song et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis
Lawrence R. Gray et al.
CELL METABOLISM (2015)
Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling
Kyle S. McCommis et al.
CELL METABOLISM (2015)
Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis
Chrysi Koliaki et al.
CELL METABOLISM (2015)
ALCAT1 Controls Mitochondrial Etiology of Fatty Liver Diseases, Linking Defective Mitophagy to Steatosis
Li Wang et al.
HEPATOLOGY (2015)
Perilipin 5 Improves Hepatic Lipotoxicity by Inhibiting Lipolysis
Chao Wang et al.
HEPATOLOGY (2015)
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver
Santhosh Satapati et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Liver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance in High Fat-Fed Mice
Michelle B. Trevino et al.
MOLECULAR ENDOCRINOLOGY (2015)
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
Rachel J. Perry et al.
SCIENCE (2015)
Decreasing mitochondrial fission alleviates hepatic steatosis in a murine model of nonalcoholic fatty liver disease
Chad A. Galloway et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man
Alexander Jais et al.
CELL (2014)
The PPARα-FGF21 Hormone Axis Contributes to Metabolic Regulation by the Hepatic JNK Signaling Pathway
Santiago Vernia et al.
CELL METABOLISM (2014)
Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
Sarah M. Turpin et al.
CELL METABOLISM (2014)
Resveratrol Does Not Benefit Patients With Nonalcoholic Fatty Liver Disease
Veronique S. Chachay et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2014)
Relationship Between Disease Severity, Hyperinsulinemia, and Impaired Insulin Clearance in Patients With Nonalcoholic Steatohepatitis
Fernando Bril et al.
HEPATOLOGY (2014)
Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease
Yuka Fukuo et al.
HEPATOLOGY RESEARCH (2014)
A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice
Joao A. G. Duarte et al.
JOURNAL OF LIPID RESEARCH (2014)
Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity
Ana Paula Arruda et al.
NATURE MEDICINE (2014)
Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
A. Gonzalez-Rodriguez et al.
CELL DEATH & DISEASE (2014)
Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
Rachel J. Perry et al.
CELL METABOLISM (2013)
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
Marc Liesa et al.
CELL METABOLISM (2013)
Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice
C. Owen et al.
DIABETOLOGIA (2013)
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
Juan Pablo Munoz et al.
EMBO JOURNAL (2013)
Mitochondrial dysfunction in ataxia-telangiectasia
Yasmine A. Valentin-Vega et al.
BLOOD (2012)
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice
John R. Mercer et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
Guillaume P. Leboucher et al.
MOLECULAR CELL (2012)
An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
Adam L. Hughes et al.
NATURE (2012)
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
David Sebastian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
Yoshihiro Inami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease
Nishanth E. Sunny et al.
CELL METABOLISM (2011)
Vitamin E and the Risk of Prostate Cancer The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Eric A. Klein et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)
2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death
Johann Grundlingh et al.
JOURNAL OF MEDICAL TOXICOLOGY (2011)
Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation
Dale W. Hailey et al.
CELL (2010)
Redox compartmentalization and cellular stress
D. P. Jones et al.
DIABETES OBESITY & METABOLISM (2010)
Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals
Patricia Iozzo et al.
GASTROENTEROLOGY (2010)
Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials
Markus Schuerks et al.
BMJ-BRITISH MEDICAL JOURNAL (2010)
Reactive Oxygen Species Enhance Insulin Sensitivity
Kim Loh et al.
CELL METABOLISM (2009)
Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress
Mirela Delibegovic et al.
DIABETES (2009)
The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria
Scot J. Stone et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Autophagy regulates lipid metabolism
Rajat Singh et al.
NATURE (2009)
Mitochondrial Dynamics in Mammalian Health and Disease
Marc Liesa et al.
PHYSIOLOGICAL REVIEWS (2009)
Redox compartmentalization in eukaryotic cells
Young-Mi Go et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Timothy R. Koves et al.
CELL METABOLISM (2008)
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig et al.
EMBO JOURNAL (2008)
Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes
Dominique Detaille et al.
LIFE SCIENCES (2008)
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
Olga Martins de Brito et al.
NATURE (2008)
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
G. M. Cereghetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
TC Meng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Biliverdin reductase:: A major physiologic cytoprotectant
DE Barañano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Share Paper
