4.6 Article

The find of COVID-19 vaccine: Challenges and opportunities

Journal

JOURNAL OF INFECTION AND PUBLIC HEALTH
Volume 14, Issue 3, Pages 389-416

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.jiph.2020.12.025

Keywords

COVID-19; SARS-CoV-2; Flatten the curve; Vaccination; Viral pandemic; Infectious diseases

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The article provides a comprehensive scientific assessment of SARS-CoV-2, emphasizing the clinical issues of the current COVID-19 pandemic, the importance of vaccine development, and discussing precautionary measures to achieve curve flattening.
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel corona virus, causing COVID-19 with Flu-like symptoms is the first alarming pandemic of the third millennium. SARS-CoV-2 belongs to beta coronavirus as Middle East respiratory syndrome coronavirus (MERS-CoV). Pandemic COVID-19 owes devastating mortality and destructively exceptional consequences on Socio-Economics life around the world. Therefore, the current review is redirected to the scientific community to owe comprehensive visualization about SARS-CoV-2 to tackle the current pandemic. As systematically shown through the current review, it indexes unmet medical problem of COVID-19 in view of public health and vaccination discovery for the infectious SARS-CoV-2; it is currently under-investigational therapeutic protocols, and next possible vaccines. Furthermore, the review extensively reports the precautionary measures to achieveCOVID-19/Flatten the curve. It is concluded that vaccines formulation within exceptional no time in this pandemic is highly recommended, via following the same protocols of previous pandemics; MERS-CoV and SARS-CoV, and excluding some initial steps of vaccination development process. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.

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