Journal
FUNGAL BIOLOGY REVIEWS
Volume 34, Issue 4, Pages 202-214Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.fbr.2020.10.003
Keywords
Aspergillus fumigatus; Azole resistance; Demethylase inhibitor; Expert meeting; Fungicide
Categories
Funding
- Royal Netherlands Society for Arts and Sciences (KNAW)
- European Confederation for Medical Mycology (ECMM)
- International Society for Human and Animal Mycology (ISHAM)
- Netherlands Society for Medical Mycology (NvMy)
- Fungicide Resistance Action Committee (FRAC)
- MRC [MR/R015600/1] Funding Source: UKRI
- NERC [NE/P000940/1, NE/P000916/1] Funding Source: UKRI
- Natural Environment Research Council [NE/P000916/1] Funding Source: researchfish
Ask authors/readers for more resources
Azole resistance is a concern for the management of diseases caused by Aspergillus fumiga-tus in humans. Azole fungicide use in the environment has been identified as a possible cause for development of resistance, which increases the complexity and number of stakeholders involved in this emerging problem. A workshop was held in Amsterdam early 2019 in which stakeholders, including medical and agricultural researchers, representatives from the government, public health, fungicide producers and end-users, reviewed the current evidence supporting environmental selection for resistance and to discuss which research and measures are needed to retain the effectiveness of the azole class for environmental and medical applications. This paper provides an overview of the latest insights and understanding of azole resistance development in the clinical setting and the wider environment. A One Health problem approach was undertaken to list and prioritize which research will be needed to provide missing evidence and to enable preventive interventions. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of British Mycological Society.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available