Related references
Note: Only part of the references are listed.Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group
Joerg Klepper et al.
EPILEPSIA OPEN (2020)
Ketogenic diets for drug-resistant epilepsy
Kirsty J. Martin-McGill et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2020)
Neuron-glia interactions in the pathophysiology of epilepsy
Dipan C. Patel et al.
NATURE REVIEWS NEUROSCIENCE (2019)
The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits
Haissa de Castro Abrantes et al.
JOURNAL OF NEUROSCIENCE (2019)
Lactate reduces epileptiform activity through HCA1 and GIRK channel activation in rat subicular neurons in an in vitro model
Pooja Jorwal et al.
EPILEPSIA (2019)
BRAIN GLUCOSE METABOLISM: INTEGRATION OF ENERGETICS WITH FUNCTION
Gerald A. Dienel
PHYSIOLOGICAL REVIEWS (2019)
The Science and Translation of Lactate Shuttle Theory
George A. Brooks
CELL METABOLISM (2018)
Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
Timothy A. Simeone et al.
NEUROPHARMACOLOGY (2018)
Glycogenolysis, an Astrocyte-Specific Reaction, is Essential for Both Astrocytic and Neuronal Activities Involved in Learning
Leif Hertz et al.
NEUROSCIENCE (2018)
The Glycolytic Metabolite, Fructose-1,6-bisphosphate, Blocks Epileptiform Bursts by Attenuating Voltage-Activated Calcium Currents in Hippocampal Slices
Li-Rong Shao et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
BAD and KATP channels regulate neuron excitability and epileptiform activity
Juan Ramon Martinez-Francois et al.
ELIFE (2018)
Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs A 30-Year Longitudinal Cohort Study
Zhibin Chen et al.
JAMA NEUROLOGY (2018)
Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development
Meir Bialer et al.
EPILEPSIA (2018)
Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). II. Drugs in more advanced clinical development
Meir Bialer et al.
EPILEPSIA (2018)
Global birth prevalence and mortality from inborn errors of metabolism: a systematic analysis of the evidence
Donald Waters et al.
JOURNAL OF GLOBAL HEALTH (2018)
Ketogenic diets for drug-resistant epilepsy
Kirsty J. Martin-McGill et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)
Glucose Transporters in Brain: In Health and in Alzheimer's Disease
Leszek Szablewski
JOURNAL OF ALZHEIMERS DISEASE (2017)
Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery
Simon G. Patching
MOLECULAR NEUROBIOLOGY (2017)
Glucose feeds the TCA cycle via circulating lactate
Sheng Hui et al.
NATURE (2017)
Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep-Wake Cycle
Jerome Clasadonte et al.
NEURON (2017)
How does the ketogenic diet induce anti-seizure effects?
Jong M. Rho
NEUROSCIENCE LETTERS (2017)
Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity
Takashi Matsui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Lactate Metabolism in Human Lung Tumors
Brandon Faubert et al.
CELL (2017)
Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake
Carlos Manlio Diaz-Garcia et al.
CELL METABOLISM (2017)
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics
Patrycja Puchalska et al.
CELL METABOLISM (2017)
Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer
Christopher J. Habrook et al.
CANCER CELL (2017)
Seizure control by decanoic acid through direct AMPA receptor inhibition
Pishan Chang et al.
BRAIN (2016)
A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors
Michael A. Rogawski
BRAIN (2016)
In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
Philipp Machler et al.
CELL METABOLISM (2016)
2-Deoxy-d-glucose enhances tonic inhibition through the neurosteroid-mediated activation of extrasynaptic GABAA receptors
Nicola Forte et al.
EPILEPSIA (2016)
Brain imaging in the assessment for epilepsy surgery
John S. Duncan et al.
LANCET NEUROLOGY (2016)
Pharmacology and structure of P2Y receptors
Ivar von Kuegelgen et al.
NEUROPHARMACOLOGY (2016)
Lactate modulates the intracellular pH sensitivity of human TREK1 channels
Swagata Ghatak et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade
P. Jourdain et al.
SCIENTIFIC REPORTS (2016)
Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: Involvement of the Akt-mTOR signaling pathway
Zhi Zhao et al.
CANCER LETTERS (2015)
Is L-lactate a novel signaling molecule in the brain?
Valentina Mosienko et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity
Trine M. Lund et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Mitochondrial dysfunction and seizures: the neuronal energy crisis
Gabor Zsurka et al.
LANCET NEUROLOGY (2015)
Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
Jae Seok Lim et al.
NATURE MEDICINE (2015)
NEURONAL NETWORKS AND ENERGY BURSTS IN EPILEPSY
Y. Wu et al.
NEUROSCIENCE (2015)
Targeting LDH enzymes with a stiripentol analog to treat epilepsy
Nagisa Sada et al.
SCIENCE (2015)
Cerebrospinal fluid findings after epileptic seizures
Anastasios Chatzikonstantinou et al.
EPILEPTIC DISORDERS (2015)
Molecular Pathogenesis of Polymerase Gamma-Related Neurodegeneration
Charalampos Tzoulis et al.
ANNALS OF NEUROLOGY (2014)
Glucose metabolism transporters and epilepsy: Only GLUT1 has an established role
Michael S. Hildebrand et al.
EPILEPSIA (2014)
ILAE Official Report: A practical clinical definition of epilepsy
Robert S. Fisher et al.
EPILEPSIA (2014)
The utility of 18F-fluorodeoxyglucose PET (FDG PET) in epilepsy surgery
Chaturbhuj Rathore et al.
EPILEPSY RESEARCH (2014)
Focal epilepsy in Glucose transporter type 1 (Glut1) defects: case reports and a review of literature
Stefan Wolking et al.
JOURNAL OF NEUROLOGY (2014)
Cerebral Creatine Deficiencies: A Group of Treatable Intellectual Developmental Disorders
Sylvia Stockler-Ipsiroglu et al.
SEMINARS IN NEUROLOGY (2014)
Lactate-mediated glia-neuronal signalling in the mammalian brain
F. Tang et al.
NATURE COMMUNICATIONS (2014)
Neuroactive peptides as putative mediators of antiepileptic ketogenic diets
Carmela Giordano et al.
FRONTIERS IN NEUROLOGY (2014)
Autophagy-dependent ATP release from dying cells via lysosomal exocytosis
Yidan Wang et al.
AUTOPHAGY (2013)
Fructose-1,6-diphosphate protects against epileptogenesis by modifying cation-chloride co-transporters in a model of amygdaloid-kindling temporal epilepticus
Yao Ding et al.
BRAIN RESEARCH (2013)
Inborn errors of creatine metabolism and epilepsy
Vincenzo Leuzzi et al.
EPILEPSIA (2013)
Cortical excitability changes correlate with fluctuations in glucose levels in patients with epilepsy
Radwa A. B. Badawy et al.
EPILEPSY & BEHAVIOR (2013)
Cerebral energy metabolism and the brain's functional network architecture: an integrative review
Louis-David Lord et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Targeting lactate metabolism for cancer therapeutics
Joanne R. Doherty et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
New avenues for anti-epileptic drug discovery and development
Wolfgang Loescher et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma
Seung-Cheol Lee et al.
NMR IN BIOMEDICINE (2013)
Lactate Modulates the Activity of Primary Cortical Neurons through a Receptor-Mediated Pathway
Luigi Bozzo et al.
PLOS ONE (2013)
The ketogenic diet: metabolic influences on brain excitability and epilepsy
Andrew Lutas et al.
TRENDS IN NEUROSCIENCES (2013)
Role of hormones and neurosteroids in epileptogenesis
Doodipala Samba Reddy
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Mitochondrial diseases and epilepsy
Laurence A. Bindoff et al.
EPILEPSIA (2012)
Glucose transporter type I deficiency syndrome: Epilepsy phenotypes and outcomes
Amanda W. Pong et al.
EPILEPSIA (2012)
Alternative diets to the classical ketogenic diet-Can we be more liberal?
Maria J. Miranda et al.
EPILEPSY RESEARCH (2012)
Sweet sixteen for ANLS
Luc Pellerin et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Epilepsy in Children-When Should We Think Neurometabolic Disease?
Radhika Dhamija et al.
JOURNAL OF CHILD NEUROLOGY (2012)
Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma
Humsa S. Venkatesh et al.
NEURO-ONCOLOGY (2012)
BAD-Dependent Regulation of Fuel Metabolism and KATP Channel Activity Confers Resistance to Epileptic Seizures
Alfredo Gimenez-Cassina et al.
NEURON (2012)
Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms
David Cheillan et al.
ORPHANET JOURNAL OF RARE DISEASES (2012)
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity
Ditte Lovatt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The ketogenic diet as a treatment paradigm for diverse neurological disorders
Carl E. Stafstrom et al.
FRONTIERS IN PHARMACOLOGY (2012)
Lactate Dehydrogenase B Is Critical for Hyperactive mTOR-Mediated Tumorigenesis
Xiaojun Zha et al.
CANCER RESEARCH (2011)
Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
Akinobu Suzuki et al.
CELL (2011)
Low blood glucose precipitates spike-and-wave activity in genetically predisposed animals
Christopher A. Reid et al.
EPILEPSIA (2011)
Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy
Takahisa Hanada et al.
EPILEPSIA (2011)
Frontier of Epilepsy Research - mTOR signaling pathway
Chang-Hoon Cho
EXPERIMENTAL AND MOLECULAR MEDICINE (2011)
Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans
Peter Rasmussen et al.
FASEB JOURNAL (2011)
A ketogenic diet suppresses seizures in mice through adenosine A1 receptors
Susan A. Masino et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Na+, K+-ATPase: Functions in the nervous system and involvement in neurologic disease
E. E. Benarroch
NEUROLOGY (2011)
Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity
L. Pellerin
DIABETES & METABOLISM (2010)
Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis
Faraaz B. Chekeni et al.
NATURE (2010)
Absence epilepsies with widely variable onset are a key feature of familial GLUT1 deficiency
S. A. Mullen et al.
NEUROLOGY (2010)
Metabolic Control of Vesicular Glutamate Transport and Release
Narinobu Juge et al.
NEURON (2010)
Fructose-1,6-diphosphate inhibits seizure acquisition in fast hippocampal kindling
Yao Ding et al.
NEUROSCIENCE LETTERS (2010)
Cancer as a metabolic disease
Thomas N. Seyfried et al.
NUTRITION & METABOLISM (2010)
Epileptic seizures: Quakes of the brain?
Ivan Osorio et al.
PHYSICAL REVIEW E (2010)
Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles
Hiroshi Hibino et al.
PHYSIOLOGICAL REVIEWS (2010)
Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: A case report
Leonilda Bilo et al.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2010)
Targeting metabolic transformation for cancer therapy
Daniel A. Tennant et al.
NATURE REVIEWS CANCER (2010)
A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy
Elizabeth G. Neal et al.
EPILEPSIA (2009)
Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81
Changlu Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Blood lactate is an important energy source for the human brain
Gerrit van Hall et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2009)
Expanded clinical and molecular spectrum of guanidinoacetate methyltransferase (GAMT) deficiency
S. U. Dhar et al.
MOLECULAR GENETICS AND METABOLISM (2009)
The anti-convulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulator
Janet L. Fisher
NEUROPHARMACOLOGY (2009)
Mitochondrial disorders in the nervous system
Salvatore DiMauro et al.
ANNUAL REVIEW OF NEUROSCIENCE (2008)
Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A
A. Matagne et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial
Elizabeth G. Neal et al.
LANCET NEUROLOGY (2008)
Seizure termination by acidosis depends on ASIC1a
Adam E. Ziemann et al.
NATURE NEUROSCIENCE (2008)
Purinergic signalling and disorders of the central nervous system
Geoffrey Burnstock
NATURE REVIEWS DRUG DISCOVERY (2008)
Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal
Anthony Accurso et al.
NUTRITION & METABOLISM (2008)
BDNF Selectively Regulates GABAA Receptor Transcription by Activation of the JAK/STAT Pathway
Ingrid V. Lund et al.
SCIENCE SIGNALING (2008)
Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats
Xiao-Yuan Lian et al.
JOURNAL OF NEUROSCIENCE (2007)
The neuropharmacology of the ketogenic diet
Adam L. Hartman et al.
PEDIATRIC NEUROLOGY (2007)
Ketogenic diet metabolites reduce firing in central neurons by opening KATP channels
Weiyuan Ma et al.
JOURNAL OF NEUROSCIENCE (2007)
2-deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure
Mireia Garriga-Canut et al.
NATURE NEUROSCIENCE (2006)
Arginine:glycine amidinotransferase (AGAT) deficiency in a newborn:: Early treatment can prevent phenotypic expression of the disease
Roberta Battini et al.
JOURNAL OF PEDIATRICS (2006)
KATP channels as molecular sensors of cellular metabolism
CG Nichols
NATURE (2006)
Current concepts - Positron-emission tomography and assessment of cancer therapy
ME Juweid et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy
MM Mirrione et al.
SYNAPSE (2006)
Extracellular metabolites in the cortex and hippocampus of epileptic patients
I Cavus et al.
ANNALS OF NEUROLOGY (2005)
Antiepileptic popular ketogenic diet: emerging twists in an ancient story
J Vamecq et al.
PROGRESS IN NEUROBIOLOGY (2005)
Postsynaptic TrkB-mediated signaling modulates excitatory and inhibitory neurotransmitter receptor clustering at hippocampal synapses
SB Elmariah et al.
JOURNAL OF NEUROSCIENCE (2004)
ATP excites interneurons and astrocytes to increase synaptic inhibition in neuronal networks
DN Bowser et al.
JOURNAL OF NEUROSCIENCE (2004)
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model
XP He et al.
NEURON (2004)
Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice
M Kawamura et al.
JOURNAL OF NEUROSCIENCE (2004)
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
BA Lynch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia - A randomized, controlled trial
WS Yancy et al.
ANNALS OF INTERNAL MEDICINE (2004)
SPECT perfusion changes during complex partial seizures in patients with hippocampal sclerosis
W Van Paesschen et al.
BRAIN (2003)
Mechanisms of neuronal hyperexcitability caused by partial inhibition of Na+-K+-ATPases in the rat CA1 hippocampal region
C Vaillend et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Altered activities of rat brain metabolic enzymes in electroconvulsive shock-induced seizures
V Erakovic et al.
EPILEPSIA (2001)
Systematic review of prediction of poor outcome in anoxic-ischaemic coma with biochemical markers of brain damage
EGJ Zandbergen et al.
INTENSIVE CARE MEDICINE (2001)
An energy budget for signaling in the grey matter of the brain
D Attwell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines
BS Dwarkanath et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Irreversible brain creatine deficiency with elevated serum and urine creatine: A creatine transporter defect?
KM Cecil et al.
ANNALS OF NEUROLOGY (2001)
Phosphofructokinase, a glycolytic regulatory enzyme has a crucial role for maintenance of synaptic activity in guinea pig hippocampal slices
XX Li et al.
NEUROSCIENCE LETTERS (2000)