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PROTEIN & CELL (2013)
Type I interferons as stimulators of DC-mediated cross-priming: impact on anti-tumor response
Giovanna Schiavoni et al.
FRONTIERS IN IMMUNOLOGY (2013)
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
Markus H. Heim
NATURE REVIEWS IMMUNOLOGY (2013)
The genetics of type I interferon in systemic lupus erythematosus
Paola G. Bronson et al.
CURRENT OPINION IN IMMUNOLOGY (2012)
Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity
Michael C. Abt et al.
IMMUNITY (2012)
Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling
Daniel J. Gough et al.
IMMUNITY (2012)
Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota
Stephanie C. Ganal et al.
IMMUNITY (2012)
The effect of combination IFN-alpha-2a with usual antituberculosis chemotherapy in non-responding tuberculosis and diabetes mellitus: a case report and review of the literature
Paul Zarogoulidis et al.
JOURNAL OF CHEMOTHERAPY (2012)
Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis
Ludovic Desvignes et al.
JOURNAL OF IMMUNOLOGY (2012)
Cutting Edge: Independent Roles for IRF-3 and IRF-7 in Hematopoietic and Nonhematopoietic Cells during Host Response to Chikungunya Infection
Clementine Schilte et al.
JOURNAL OF IMMUNOLOGY (2012)
Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis
Xuan Feng et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2012)
Interferon Response Factors 3 and 7 Protect against Chikungunya Virus Hemorrhagic Fever and Shock
Penny A. Rudd et al.
JOURNAL OF VIROLOGY (2012)
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
Nirmal Robinson et al.
NATURE IMMUNOLOGY (2012)
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape
Bradley N. Bidwell et al.
NATURE MEDICINE (2012)
Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis
Tom H. M. Ottenhoff et al.
PLOS ONE (2012)
Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection
Kathrin Gibbert et al.
PLOS PATHOGENS (2012)
Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease
Frederick J. Schnell et al.
PLOS PATHOGENS (2012)
The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity
Byron C. Burnette et al.
CANCER RESEARCH (2011)
Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
Christoph Thomas et al.
CELL (2011)
Binding and activity of all human alpha interferon subtypes
Thomas B. Lavoie et al.
CYTOKINE (2011)
Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection
Ashraful Haque et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Human gene expression profiles of susceptibility and resistance in tuberculosis
J. Maertzdorf et al.
GENES AND IMMUNITY (2011)
Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection
Katrin D. Mayer-Barber et al.
IMMUNITY (2011)
Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome
Shruti Sharma et al.
IMMUNITY (2011)
Beta Interferon Suppresses the Development of Experimental Cerebral Malaria
Craig N. Morrell et al.
INFECTION AND IMMUNITY (2011)
Efficacy and Safety of Combination Therapy of Natural Human Interferon Beta and Ribavirin in Chronic Hepatitis C patients
Yasuji Arase et al.
INTERNAL MEDICINE (2011)
Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2
Rebecca A. R. Piganis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
Mark S. Diamond et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Evolutionary genetic dissection of human interferons
Jeremy Manry et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice
Mohammad Salem et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Beta Interferon Controls West Nile Virus Infection and Pathogenesis in Mice
Helen M. Lazear et al.
JOURNAL OF VIROLOGY (2011)
Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2
Hui Zheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment
Doron Levin et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease
Margarita Dominguez-Villar et al.
NATURE MEDICINE (2011)
Leishmaniasis: complexity at the host-pathogen interface
Paul Kaye et al.
NATURE REVIEWS MICROBIOLOGY (2011)
USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response
Veronique Francois-Newton et al.
PLOS ONE (2011)
Type I IFN Promotes IL-10 Production from T Cells to Suppress Th17 Cells and Th17-Associated Autoimmune Inflammation
Lixia Zhang et al.
PLOS ONE (2011)
Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence
Brian M. Sullivan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Type I Interferon Production Induced by Streptococcus pyogenes-Derived Nucleic Acids Is Required for Host Protection
Nina Gratz et al.
PLOS PATHOGENS (2011)
Neutrophils responsive to endogenous IFN-β regulate tumor angiogenesis and growth in a mouse tumor model
Jadwiga Jablonska et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population
Lis R. V. Antonelli et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells
Clementine Schilte et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Biochemical Monitoring of the Early Endocytic Traffic of the Type I Interferon Receptor
Beatrice Payelle-Brogard et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2010)
The TLR7 agonist, imiquimod, increases IFN-β production and reduces the severity of experimental autoimmune encephalomyelitis
Kate O'Brien et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
Matthew P. R. Berry et al.
NATURE (2010)
T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis
Robert C. Axtell et al.
NATURE MEDICINE (2010)
Developing vaccines to combat hookworm infection and intestinal schistosomiasis
Peter J. Hotez et al.
NATURE REVIEWS MICROBIOLOGY (2010)
Interferon-alpha: A Therapeutic Target in Systemic Lupus Erythematosus
Mary K. Crow
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA (2010)
Neutralization of Interferon-alpha/beta-Inducible Genes and Downstream Effect in a Phase I Trial of an Anti-Interferon-alpha Monoclonal Antibody in Systemic Lupus Erythematosus
Yihong Yao et al.
ARTHRITIS AND RHEUMATISM (2009)
Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
Philipp A. Lang et al.
BLOOD (2009)
Characterization of the bovine type I IFN locus: rearrangements, expansions, and novel subfamilies
Angela M. Walker et al.
BMC GENOMICS (2009)
A type I interferon signature in monocytes is associated with poor response to interferon-β in multiple sclerosis
M. Comabella et al.
BRAIN (2009)
Anti-retroviral effects of type I IFN subtypes in vivo
Nicole Gerlach et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Characterization and Virus-Induced Expression Profiles of the Porcine Interferon-ω Multigene Family
Xin Zhao et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2009)
IFN-beta improves BCG immunogenicity by acting on DC maturation
Elena Giacomini et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities
Ignacio Moraga et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Differential Regulation of Human Interferon A Gene Expression by Interferon Regulatory Factors 3 and 7
Pierre Genin et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
IFNα activates dormant haematopoietic stem cells in vivo
Marieke A. G. Essers et al.
NATURE (2009)
Genetics of Type 1A Diabetes.
Vincenzo Sepe et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: Role of intracellular osteopontin
Mari L. Shinohara et al.
IMMUNITY (2008)
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
Marco Prinz et al.
IMMUNITY (2008)
Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection
Stephane Daffis et al.
JOURNAL OF VIROLOGY (2008)
Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis:: interferon-β treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression
M. Krakauer et al.
MULTIPLE SCLEROSIS JOURNAL (2008)
A mouse model for chikungunya:: Young age and inefficient type-I interferon signaling are risk factors for severe disease
Therese Couderc et al.
PLOS PATHOGENS (2008)
Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus
Matteo Iannacone et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Interferon-α initiates type 1 diabetes in nonobese diabetic mice
Qing Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Comparable potency of IFNα2 and IFNß on immediate JAK/STAT activation but differential down-regulation of IFNAR2
Zrinka Marijanovic et al.
BIOCHEMICAL JOURNAL (2007)
Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus
C. C. Khor et al.
GENES AND IMMUNITY (2007)
Adjunctive treatment of disseminated Mycobacterium avium complex infection with interferon alpha-2b in a patient with complete interferon-gamma receptor R1 deficiency
Carla M. Ward et al.
EUROPEAN JOURNAL OF PEDIATRICS (2007)
Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection
Oleg Garifulin et al.
PLOS GENETICS (2007)
Evolution of the interferon alpha gene family in eutherian mammals
Christopher H. Woelk et al.
GENE (2007)
The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation
Diane Ordway et al.
JOURNAL OF IMMUNOLOGY (2007)
An atomic model of the interferon-β enhanceosome
Daniel Panne et al.
CELL (2007)
Type I IFN contributes to NK cell homeostasis, activation, and antitumor function
Jeremy B. Swann et al.
JOURNAL OF IMMUNOLOGY (2007)
Recombinant human IFN-α inhibits cerebral malaria and reduces parasite burden in mice
Ana Margarida Vigario et al.
JOURNAL OF IMMUNOLOGY (2007)
The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
Sarah A. Stanley et al.
JOURNAL OF IMMUNOLOGY (2007)
Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria
Giuseppe Mancuso et al.
JOURNAL OF IMMUNOLOGY (2007)
Cloning and characterization of a novel feline IFN-ω
Li-Min Yang et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2007)
Protective role of beta interferon in host defense against influenza A virus
Iris Koerner et al.
JOURNAL OF VIROLOGY (2007)
Cutting edge:: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-β
Tarik Touil et al.
JOURNAL OF IMMUNOLOGY (2006)
Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors
Marta Marchetti et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
Oxana A. Malakhova et al.
EMBO JOURNAL (2006)
Effects of type I interferons on friend retrovirus infection
N Gerlach et al.
JOURNAL OF VIROLOGY (2006)
Inquiring into the differential action of interferons (IFNs):: an IFN-α2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-β
DA Jaitin et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKε
A Civas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
Kenya Honda et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Alpha/beta interferon protects against lethal west nile virus infection by restricting cellular tropism and enhancing neuronal survival
MA Samuel et al.
JOURNAL OF VIROLOGY (2005)
Hypervirulent M-tuberculosis W/Beijing strains upregulate type IIFNs and increase expression of negative regulators of the Jak-Stat pathway
C Manca et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2005)
Mutational analysis of the IFNAR1 binding site on IFNα2 reveals the architecture of a weak ligand-receptor binding-site
LC Roisman et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Interferon-α and -β differentially regulate osteoclastogenesis:: Role of differential induction of chemokine CXCL11 expression
LFL Coelho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors
GR Angstreich et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
A critical function for type I interferons in cancer immunoediting
GP Dunn et al.
NATURE IMMUNOLOGY (2005)
Mechanisms of type-I- and type-II-interferon-mediated signalling
LC Platanias
NATURE REVIEWS IMMUNOLOGY (2005)
IRF-7 is the master regulator of type-I interferon-dependent immune responses
K Honda et al.
NATURE (2005)
Cross-regulation of TNF and IFN-α in autoimmune diseases
AK Palucka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
KS Lang et al.
NATURE MEDICINE (2005)
Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in dendritic cells
E Aksoy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes
V Auerbuch et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to listeria infection
JA Carrero et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Type I interferon production enhances susceptibility to Listeria monocytogenes infection
RM O'Connell et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Characterization of the murine alpha interferon gene family
V van Pesch et al.
JOURNAL OF VIROLOGY (2004)
Characterization of the type I interferon locus and identification of novel genes
MP Hardy et al.
GENOMICS (2004)
Interferons, interferon-like cytokines, and their receptors
S Pestka et al.
IMMUNOLOGICAL REVIEWS (2004)
IFN-α priming results in a gain of proinflammatory function by IL-10:: Implications for systemic lupus erythematosus pathogenesis
MN Sharif et al.
JOURNAL OF IMMUNOLOGY (2004)
Autoimmunity through cytokine-induced dendritic cell activation
J Banchereau et al.
IMMUNITY (2004)
Microarray analysis of interferon-regulated genes in SLE
MK Crow et al.
AUTOIMMUNITY (2003)
Review article: type 1 diabetes mellitus in patients with chronic hepatitis C before and after interferon therapy
P Fabris et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2003)
Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in The Gambia
C Aucan et al.
GENES AND IMMUNITY (2003)
IFN-β gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis
I Teige et al.
JOURNAL OF IMMUNOLOGY (2003)
Systemic IFN-β treatment induces apoptosis of peripheral immune cells in MS patients
P Gniadek et al.
JOURNAL OF NEUROIMMUNOLOGY (2003)
Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis
Z von Marschall et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
L Bennett et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
EC Baechler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The pathogenesis of streptococcal infections: From tooth decay to meningitis
TJ Mitchell
NATURE REVIEWS MICROBIOLOGY (2003)
IFN-lambda s mediate antiviral protection through a distinct class II cytokine receptor complex
SV Kotenko et al.
NATURE IMMUNOLOGY (2003)
Production of type IIFN sensitizes macrophages to cell death induced by Listeria monocytogenes
S Stockinger et al.
JOURNAL OF IMMUNOLOGY (2002)
A pilot study of β-interferon for treatment of patients with chronic hepatitis B who failed to respond to α-interferon
R Muñoz et al.
JOURNAL OF HEPATOLOGY (2002)
Regulatory effect of IFN-κ, a novel type IIFN, on cytokine production by cells of the innate immune system
B Nardelli et al.
JOURNAL OF IMMUNOLOGY (2002)
Dendritic cells, BAFF, and APRIL: Innate players in adaptive antibody responses
ICM MacLennan et al.
IMMUNITY (2002)
Alpha/beta interferon impairs the ability of human macrophages to control growth of Mycobacterium bovis BCG
F Bouchonnet et al.
INFECTION AND IMMUNITY (2002)
Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription
P Morin et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus
P Blanco et al.
SCIENCE (2001)
Interferon-κ, a novel type I interferon expressed in human keratinocytes
DW LaFleur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Constitutive IFN-α/β signal for efficient IFN-α/β gene induction by virus
N Hata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Inhibition of Plasmodium yoelii blood-stage malaria by interferon α through the inhibition of the production of its target cell, the reticulocyte
AM Vigário et al.
BLOOD (2001)
Effect of early interferon treatment on conversion to definite multiple sclerosis:: a randomised study
G Comi et al.
LANCET (2001)
Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β
C Manca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface
J Piehler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-α)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-β) treatment
V Özenci et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2000)
Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon
R Deonarain et al.
JOURNAL OF VIROLOGY (2000)