Journal
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
Volume 11, Issue 4, Pages 1340-1351Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s13346-021-00913-w
Keywords
Chitosan; Nanoparticle; Vaccine vector; Wound dressing; Infectious disease
Funding
- National Natural Science Foundation of China [51703105, 51829301]
- Natural Science Foundation of Shandong Province [ZR2017BEM012]
- Beijing Outstanding Young Scientist Program [BJJWZYJH01201910010024]
- Fundamental Research Funds for the Central Universities [XK1802-2]
- China Postdoctoral Science Foundation [2018M630752]
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Infectious diseases like COVID-19, SARS, Ebola, and AIDS pose a global health threat, leading researchers to develop new antiviral and antibacterial drugs. Natural material chitosan, when used in collaboration with traditional medicine, has shown to enhance anti-infection capabilities.
Infectious diseases, such as the coronavirus disease-19, SARS virus, Ebola virus, and AIDS, threaten the health of human beings globally. New viruses, drug-resistant bacteria, and fungi continue to challenge the human efficacious drug bank. Researchers have developed a variety of new antiviral and antibacterial drugs in response to the infectious disease crisis. Meanwhile, the development of functional materials has also improved therapeutic outcomes. As a natural material, chitosan possesses good biocompatibility, bioactivity, and biosafety. It has been proven that the cooperation between chitosan and traditional medicine greatly improves the ability of anti-infection. This review summarized the application and design considerations of chitosan-composed systems for the treatment of infectious diseases, looking forward to providing the idea of infectious disease therapy.
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