Adverse effects of atrazine on blood parameters, biochemical profile and genotoxicity of snow trout (Schizothorax plagiostomus)

This study was conducted to evaluate the adverse effects of atrazine on hematology, biochemistry and genotoxicity of snow trout (Schizothorax plagiostomus). Almost all treated groups presented considerably (P<0.05) lesser values of hematocrit, hemoglobin, WBC, RBC, MCH, MCHC, monocytes and lymphocytes while significantly higher values of HCT and platelets are observed. A Significant decrease is observed in sodium, calcium, potassium, phosphorous, triglycerides, creatinine, urea, and total protein contents whereas, a significant increase is observed in cholesterol and glucose level. Significant (P<0.05) alter-ations are observed in enzyme activities of all treated groups. DNA damage was observed at the concen-trations (24ppm). Results showed that Comet assay is reliable for evaluating the toxicity and is helpful in environmental monitoring programs. (c) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Automated summary

This study evaluated the adverse effects of atrazine on snow trout, showing significant changes in hematological, biochemical parameters, and genotoxicity. Exposure to atrazine resulted in alterations in blood parameters, as well as DNA damage, indicating potential toxicity in the tested fish species.