4.2 Article

Progress towards elimination of lymphatic filariasis in the Americas region

Journal

INTERNATIONAL HEALTH
Volume 13, Issue -, Pages S33-S38

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/inthealth/ihaa048

Keywords

Americas region; elimination program; lymphatic filariasis; Wuchereria bancrofti

Funding

  1. MSD
  2. GSK
  3. Eisai

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In South and Central America, progress has been made in eliminating LF transmission, with countries like Brazil, Dominican Republic, Guyana, and Haiti achieving important milestones such as stopping mass drug administration and interrupting transmission in certain endemic areas. Efforts should continue to improve morbidity management to prevent disabilities in affected populations.
In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad and Tobago were removed from the World Health Organization list in 2011. The remaining countries, Brazil, Dominican Republic, Guyana and Haiti, have achieved important progress in recent years. Brazil was the first country in the Americas to stop mass drug administration (MDA) and to establish post-MDA surveillance. Dominican Republic stopped MDA in all LF-endemic foci: La Cienaga and Southwest passed the third Transmission Assessment Survey (TAS) and the Eastern focus passed TAS-1 in 2018. Haiti passed the TAS and interrupted transmission in >80% of endemic communes, achieving effective drug coverage. Guyana implemented effective coverage in MDAs in 2017 and 2018 and in 2019 scaled up the treatment for 100% of the geographical region, introducing ivermectin in the MDA in order to achieve LF elimination by the year 2026. The Americas region is on its way to eliminating LF transmission. However, efforts should be made to improve morbidity management to prevent disability of the already affected populations.

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